SCHEMBL141584

SCHEMBL141584

CNC1CCCCC1.CO[SiH](OC)OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 1/20 0.38
NPSR1 Q6W5P4 1/20 0.35
POLB P06746 1/20 0.33
EPHX2 P34913 2/20 0.32
SIGMAR1 Q99720 3/20 0.32
GLA P06280 1/20 0.31
EPHX1 P07099 5/20 0.31
CYP3A4 P08684 2/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH4 P08319 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA7 P43166 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18141889 0.98 ALDH1A1 (0.36) ALDH1A1HSD17B10NPSR1POLBEPHX2
SCHEMBL20985093 0.98 ALDH1A1 (0.33) ALDH1A1HSD17B10NPSR1POLB
SCHEMBL28788337 0.87 KDM1A (0.31)
SCHEMBL1516307 0.84 ALDH1A1 (0.36) ALDH1A1HSD17B10NPSR1EPHX2SIGMAR1
SCHEMBL13166298 0.82 ALDH1A1 (0.53) ALDH1A1HSD17B10EPHX2SIGMAR1EPHX1
SCHEMBL1148684 0.82
SCHEMBL3036481 0.82 ALDH1A1 (0.53) ALDH1A1HSD17B10EPHX2SIGMAR1EPHX1
SCHEMBL3035987 0.82 ALDH1A1 (0.53) ALDH1A1HSD17B10EPHX2SIGMAR1EPHX1
SCHEMBL13166302 0.82 ALDH1A1 (0.53) ALDH1A1HSD17B10EPHX2SIGMAR1EPHX1
SCHEMBL1485899 0.82 ALDH1A1 (0.53) ALDH1A1HSD17B10EPHX2SIGMAR1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12565562-B2 Silane terminated polyether emulsions for coating applications WACKER CHEMIE AG (DE) 2026-03-03 US claimed
CN-114787238-B Silane-terminated polyether emulsions for coating applications 瓦克化学股份公司 2024-05-24 CN claimed
EP-3476876-B1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS MOMENTIVE PERFORMANCE MAT INC (US) 2023-08-09 EP claimed
EP-4073142-B1 SILANE TERMINATED POLYETHER EMULSIONS FOR COATING APPLICATIONS WACKER CHEMIE AG (DE) 2023-06-14 EP claimed
EP-3328958-B1 USE OF A SINGLE OR MULTI COMPONENT SYSTEM FOR SECURING ANCHORING MEANS FISCHERWERKE GMBH & CO KG (DE) 2022-10-05 EP claimed
CN-114787238-A Silane terminated polyether emulsions for coating applications 瓦克化学股份公司 2022-07-22 CN claimed
EP-3476876-A1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS Momentive Performance Materials Inc. (US) 2019-05-01 EP claimed
EP-3328958-A2 USE OF A SINGLE OR MULTI COMPONENT SYSTEM FOR SECURING ANCHORING MEANS fischerwerke GmbH & Co. KG (DE) 2018-06-06 EP claimed
EP-3083738-A1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS Momentive Performance Materials Inc. (US) 2016-10-26 EP claimed
EP-2435502-B1 CURABLE SILYL-GROUP CONTAINING COMPOSITIONS AND ITS USE EVONIK DEGUSSA GMBH (DE) 2016-10-19 EP claimed
US-9321878-B2 Process for the preparation of silylated polyurethane polymers using titanium-containing and zirconium-containing catalysts MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-04-26 US claimed
WO-2015095029-A1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-06-25 WO claimed
US-20150166719-A1 PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-06-18 US claimed
US-8974627-B2 Curable compositions containing silyl groups, and use thereof EVONIK DEGUSSA GMBH (DE) 2015-03-10 US claimed
US-20120067520-A1 Curable Compositions Containing Silyl Groups, And Use Thereof EVONIK GOLDSCHMIDT GMBH (DE) 2012-03-22 US claimed
EP-2189485-B1 Polyurethane composition comprising alpha-silane having anisostropic material properties SIKA TECHNOLOGY AG (CH) 2011-02-16 EP claimed
US-12637599-B2 Two-component polyurethane adhesive composition for film lamination in hot filling application HENKEL AG & CO. KGAA (DE) 2026-05-26 US disclosed
EP-4727993-A1 ADHESION PROMOTER FOR POLYSULFIDE- AND POLYTHIOETHER-BASED SEALANTS Chemetall GmbH (DE) 2026-04-22 EP disclosed
WO-2005059005-A1 MOISTURE CURABLE HIGH STRENGTH, FLEXIBLE RTV ORGANIC COPOLYMER COMPOSITIONS AND METHODS OF PREPARATION HENKEL CORPORATION (US) 2005-06-30 WO disclosed
US-20050131188-A1 Moisture curable high strength, flexible RTV organic copolymer compositions and methods of preparation HENKEL LOCTITE CORPORATION 2005-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12565562-B2 Silane terminated polyether emulsions for coating applications SPTAN1, SPTBN1, SGMS1 ALDH1A1 1991/4885HSD17B10 916/4885NPSR1 2337/4885
US-12637599-B2 Two-component polyurethane adhesive composition for film lamination in hot filling application EPHX2, GJB2, GJA1 ALDH1A1 177/4885HSD17B10 44/4885NPSR1 3523/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.