Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13128921 | 0.86 | MAPT (0.51) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14160305 | 0.78 | PTK2B (0.52) | L3MBTL1ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL13128920 | 0.76 | PTK2B (0.63) | L3MBTL1ALDH1A1MEN1KMT2ARAD52 | |
| SCHEMBL2740945 | 0.75 | CRHBP (0.51) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6861454 | 0.73 | RXRA (0.55) | L3MBTL1ALDH1A1HPGDHSD17B10RAD52 | |
| SCHEMBL3557287 | 0.72 | SLC16A3 (0.64) | L3MBTL1ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL13128919 | 0.72 | MEN1 (0.46) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL3553525 | 0.72 | ALDH1A1 (0.60) | L3MBTL1ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL13128926 | 0.71 | IDO1 (0.57) | ALDH1A1HPGDMEN1KMT2AHTT | |
| SCHEMBL13128924 | 0.70 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2AMETAP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249135-A1 | SULFONAMIDES AND THEIR USE AS A MEDICAMENT | THE GENETICS COMPANY, INC. (CH) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249135-A1 | SULFONAMIDES AND THEIR USE AS A MEDICAMENT | BCOR, CBR3, SULT1E1 | L3MBTL1 1642/4885ALDH1A1 3484/4885HPGD 2067/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.