SCHEMBL1416613

SCHEMBL1416613

CNC(=O)N(C)c1[c]cccc1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.35
LMNA P02545 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 1/20 0.33
RECQL P46063 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MTOR P42345 1/20 0.33
CYP3A4 P08684 1/20 0.32
PKM P14618 1/20 0.31
KMT2A Q03164 2/20 0.31
GAA P10253 1/20 0.31
MALT1 Q9UDY8 1/20 0.30
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16294301 0.79 RAB9A (0.36) KMT2AHSP90AA1HSP90AB1NPC1RAB9A
SCHEMBL95841 0.79 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2KMT2AGAANPC1
SCHEMBL2535686 0.79 TSHR (0.42) LMNAL3MBTL1ALDH1A1PKMKMT2A
SCHEMBL8127161 0.78 NPC1 (0.34) ALDH1A1KMT2AMALT1HSP90AA1HSP90AB1
SCHEMBL1416233 0.78 ALOX5 (0.34) L3MBTL1ALDH1A1RECQLSMN1; SMN2CYP3A4
SCHEMBL3758920 0.78 ROCK2 (0.42) ROCK2LMNASMN1; SMN2CYP3A4KMT2A
SCHEMBL2537879 0.75 NPC1 (0.33) ALDH1A1SMN1; SMN2CYP3A4PKMKMT2A
SCHEMBL482524 0.75 KMT2A (0.45) LMNAALDH1A1RECQLSMN1; SMN2KMT2A
SCHEMBL7839570 0.74 KDM4E (0.38) ALDH1A1KMT2ANPC1RAB9A
SCHEMBL7838941 0.74 AOC3 (0.41) KMT2AGAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2165830-B1 Lithographic printing plate precursor and printing method using the same FUJIFILM CORP (JP) 2011-03-16 EP disclosed
US-20100071574-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
EP-2165830-A1 Lithographic printing plate precursor and printing method using the same Fujifilm Corporation (JP) 2010-03-24 EP disclosed
EP-0322553-A1 Silver halide photographic light-sensitive material and a process for forming a high contrastphotographic image DAINIPPON INK AND CHEMICALS, INC. (JP) 1989-07-05 EP disclosed