Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29359500 | 0.91 | HSD11B1 (0.37) | HSD11B1CYP2A6KDM4EKMT2APKM | |
| SCHEMBL29749791 | 0.91 | HSD11B1 (0.37) | HSD11B1CYP2A6KDM4EKMT2APKM | |
| SCHEMBL307038 | 0.91 | HSD11B1 (0.37) | HSD11B1CYP2A6KDM4EKMT2APKM | |
| SCHEMBL15926080 | 0.85 | AKT1 (0.34) | HSD11B1KDM4EKMT2APKMPTGS1 | |
| SCHEMBL13645037 | 0.84 | HSD11B1 (0.37) | HSD11B1CYP2A6KDM4EKMT2APKM | |
| SCHEMBL13707049 | 0.83 | HSD11B1 (0.38) | HSD11B1CYP2A6KMT2ALMNAPTGS1 | |
| SCHEMBL30358509 | 0.83 | L3MBTL1 (0.39) | HSD11B1KDM4EKMT2ALMNAL3MBTL1 | |
| SCHEMBL3094986 | 0.83 | L3MBTL1 (0.39) | HSD11B1KDM4EKMT2ALMNAL3MBTL1 | |
| SCHEMBL16355187 | 0.82 | KDM4E (0.43) | KDM4ELMNAGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL16355186 | 0.82 | KDM4E (0.43) | KDM4ELMNAGAAL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7374863-B2 | Polyurethane binder, photoinitiator, and acrylic acid; for use as image recording layer of negative lithographic printing plate precursor; drawing with laser light | FUJIFILM CORPORATION (JP) | 2008-05-20 | — | — | US | disclosed |
| US-7374863-B2 | Polyurethane binder, photoinitiator, and acrylic acid; for use as image recording layer of negative lithographic printing plate precursor; drawing with laser light | FUJIFILM CORPORATION (JP) | 2008-05-20 | — | — | US | disclosed |