Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4843983 | 0.90 | RAB9A (0.41) | MAPTRAB9ANPC1HTTCYP1A2 | |
| SCHEMBL4846988 | 0.82 | MAPT (0.38) | MAPTL3MBTL1RAB9AALDH1A1GLA | |
| SCHEMBL4845901 | 0.78 | ABCG2 (0.42) | TGM2ALDH1A1HPGDTSHRMAPK1 | |
| SCHEMBL4842742 | 0.77 | RAB9A (0.38) | MAPTTGM2RAB9ANPC1CYP1A2 | |
| SCHEMBL4843746 | 0.77 | RAB9A (0.38) | MAPTMEN1KMT2ATGM2RAB9A | |
| SCHEMBL14181546 | 0.76 | TGM2 (0.37) | MAPTMEN1KMT2APSMD14L3MBTL1 | |
| SCHEMBL4841022 | 0.76 | CDYL2 (0.38) | MAPTTGM2RAB9ANPC1HTT | |
| SCHEMBL4841185 | 0.76 | TGM2 (0.37) | MAPTTGM2RAB9ANPC1HTT | |
| SCHEMBL14181753 | 0.76 | RAB9A (0.36) | MAPTTGM2RAB9ANPC1CYP1A2 | |
| SCHEMBL4844537 | 0.76 | PGR (0.38) | MAPTRAB9ANPC1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378428-B2 | Nitrogen-containing bicyclic compounds and drugs containing the same as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-05-27 | — | — | US | disclosed |