Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.50 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK3 | P49761 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182734 | 1.00 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2GAAMAPT | |
| SCHEMBL14182730 | 0.91 | TP53 (0.55) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14182696 | 0.91 | TP53 (0.55) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14182749 | 0.91 | TP53 (0.55) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14182631 | 0.91 | TP53 (0.55) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL14182906 | 0.90 | GSK3A (0.52) | SMN1; SMN2GSK3AGSK3BCLK2CLK3 | |
| SCHEMBL14182712 | 0.89 | ALDH1A1 (0.47) | GAAMAPTALDH1A1KMT2ATP53 | |
| SCHEMBL14182716 | 0.89 | MAOA (0.54) | RAB9ANPC1GAAMAPTMEN1 | |
| SCHEMBL14182737 | 0.89 | MAOA (0.54) | RAB9ANPC1GAAMAPTMEN1 | |
| SCHEMBL14182731 | 0.87 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |