Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182726 | 0.91 | ROCK2 (0.44) | RAB9ANPC1MAOBMAOAKMT2A | |
| SCHEMBL14182735 | 0.91 | MAOA (0.52) | PTPN1RAB9ANPC1MAOBMAOA | |
| SCHEMBL14182724 | 0.91 | MAOA (0.52) | PTPN1RAB9ANPC1MAOBMAOA | |
| SCHEMBL14182719 | 0.89 | MAOA (0.52) | PTPN1RAB9ANPC1MAOBMAOA | |
| SCHEMBL14182765 | 0.89 | KCNQ2 (0.53) | RAB9ANPC1MAOBMAOAKMT2A | |
| SCHEMBL14182745 | 0.89 | NAMPT (0.44) | MAOBMAOAKMT2AMAPT | |
| SCHEMBL14182720 | 0.89 | NAMPT (0.44) | MAOBMAOAKMT2AMAPT | |
| SCHEMBL14182740 | 0.88 | MAOB (0.55) | RAB9ANPC1MAOBMAOAKMT2A | |
| SCHEMBL14182837 | 0.87 | RAB9A (0.44) | PTPN1RAB9ANPC1MAOBMAOA | |
| SCHEMBL14182774 | 0.87 | MAOA (0.56) | PTPN1PTPN11RAB9ANPC1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |