Sugi Predict

Sugi Predict / Compounds / SCHEMBL141870

SCHEMBL141870

SCHEMBL141870

c1ccc(Oc2cccs2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LTA4H P09960 5/20 0.50
▸ TSHR P16473 1/20 0.50
▸ ATM Q13315 1/20 0.40
▸ NR1H2 P55055 1/20 0.39
▸ BAX Q07812 1/20 0.39
▸ MAOA P21397 1/20 0.39
▸ PARP10 Q53GL7 1/20 0.38
▸ NPC1 O15118 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ MAOB P27338 1/20 0.35
▸ CA1 P00915 1/20 0.35
▸ CA2 P00918 1/20 0.35
▸ CTNNB1 P35222 1/20 0.35
▸ MGMT P16455 1/20 0.35
▸ CA4 P22748 1/20 0.35
▸ APP P05067 1/20 0.34
▸ BACE1 P56817 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8471918 0.90 MGMT (0.37) LTA4HTSHRATMNR1H2BAX
Sulfamide SCHEMBL2487759 0.88 CA1 (0.47) LTA4HTSHRATMMAOAPARP10
SCHEMBL9000800 0.82 MAOA (0.36) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL2222946 0.82 LTA4H (0.33) LTA4HTSHRATMNR1H2BAX
SCHEMBL28400541 0.82 LTA4H (0.36) LTA4HTSHRNPC1RAB9AKMT2A
SCHEMBL251357 0.82 MGMT (0.40) TSHRATMNPC1RAB9AKMT2A
Hydrochloric Acid SCHEMBL10802213 0.81 LTA4H (0.32) LTA4HTSHRATMNR1H2BAX
SCHEMBL2876554 0.80 APP (0.33) MGMTAPPBACE1
SCHEMBL8124374 0.80 MAOA (0.43) LTA4HMAOARAB9AKMT2AMAOB
SCHEMBL9479303 0.80 GAA (0.47) NPC1RAB9AKMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 692 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112300143-A Organic compound based on carbazole as core and application thereof 江苏三月光电科技有限公司 2021-02-02 — — CN claimed
CN-112300144-A Organic compound based on carbazole as core and application of organic compound in OLED 江苏三月光电科技有限公司 2021-02-02 — — CN claimed
US-20140231702-A1 Cobalt Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts DOW CORNING CORPORATION 2014-08-21 — — US claimed
EP-2758417-A2 COBALT CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS Dow Corning Corporation (US) 2014-07-30 — — EP claimed
CN-103946228-A Cobalt containing hydrosilylation catalysts and compositions containing the catalysts DOW CORNING 2014-07-23 — — CN claimed
US-20140182483-A1 Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts DOW CORNING CORPORATION 2014-07-03 — — US claimed
WO-2013043783-A2 COBALT CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2013-03-28 — — WO claimed
CN-102762630-A Green soluble conjugated polymers with high carrier mobility UNIV FLORIDA 2012-10-31 — — CN claimed
EP-0162706-B1 POLYMER FILM WITH CONDUCTIVE PATTERN AND METHOD OF MANUFACTURING THE SAME NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-02-27 — — EP claimed
EP-0236913-A2 Aryl-azolylmethyl-benzocyclo-alkene derivatives, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-16 — — EP claimed
CN-118561835-B TADF guiding modification endoplasmic reticulum targeting photosensitizer and application thereof in tumor immunotherapy 山东第二医科大学 2024-10-18 — — CN disclosed
CN-118561835-A TADF guiding modification endoplasmic reticulum targeting photosensitizer and application thereof in tumor immunotherapy 山东第二医科大学 2024-08-30 — — CN disclosed
CN-113937235-B Organic light-emitting diode device comprising light improvement layer and application thereof 江苏三月科技股份有限公司 2024-08-16 — — CN disclosed
CN-113677364-B Pharmaceutical compositions comprising anti-191P 4D12 antibody drug conjugates and methods of use thereof 艾更斯司股份有限公司 2024-07-05 — — CN disclosed
CN-118265715-A Organic compound and organic electroluminescent device comprising the same 材料科学有限公司 2024-06-28 — — CN disclosed
US-4539420-A Optically active 1-aromatic-group-substituted-1-alkanones and methods for their manufacture SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1985-09-03 — — US disclosed
EP-0151702-A2 Alpha-hydroxyketone acetals SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1985-08-21 — — EP disclosed
EP-0067698-A2 Optically active 1-aromatic-group-substituted-1-alkanones and methods for their manufacture SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1982-12-22 — — EP disclosed
EP-0048136-A2 Process for preparing alpha-aromatic group substituted alkanoic acids or esters thereof SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) 1982-03-24 — — EP disclosed
US-4282246-A Antidiabetic furancarboxylic and thiphenecarboxylic acids PFIZER INC. (US) 1981-08-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140231702-A1 Cobalt Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts HIRA, CROCC, GYPA LTA4H 1187/4885TSHR 4151/4885ATM 1052/4885
US-20140182483-A1 Titanium Containing Hydrosilylation Catalysts And Compositions Containing The Catalysts ITGA1, TMT1A, ITGA2 LTA4H 478/4885TSHR 2404/4885ATM 995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.