Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.54 |
| ▸ | THRA | P10827 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192593 | 0.86 | ALDH5A1 (0.41) | THRBTHRAKMT2AMEN1ALDH1A1 | |
| SCHEMBL14192330 | 0.82 | THRB (0.81) | THRBTHRAKMT2AMEN1ACACB | |
| SCHEMBL14192426 | 0.78 | THRB (0.74) | THRBTHRAKMT2AMEN1ACACB | |
| SCHEMBL14192418 | 0.78 | THRB (0.74) | THRBTHRAKMT2AMEN1ACACB | |
| SCHEMBL14219187 | 0.77 | ALDH5A1 (0.43) | THRBTHRAKMT2AMEN1ALDH1A1 | |
| SCHEMBL14192583 | 0.76 | RARB (0.45) | THRBTHRAKMT2AMEN1 | |
| SCHEMBL14192575 | 0.74 | THRB (0.65) | THRBTHRAKMT2AMEN1ALDH1A1 | |
| SCHEMBL4904680 | 0.73 | THRB (1.00) | THRBTHRAKMT2AMEN1NPC1 | |
| SCHEMBL1493916 | 0.73 | THRB (0.83) | THRBTHRAKMT2AMEN1 | |
| SCHEMBL14192556 | 0.71 | THRB (0.61) | THRBTHRAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |