SCHEMBL14194366

SCHEMBL14194366

CCOC(=O)/C(C(=O)C(F)(F)F)=C(/C)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLO1 Q04760 1/20 0.38
ALDH1A1 P00352 4/20 0.38
LMNA P02545 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ACHE P22303 8/20 0.38
CES2 O00748 6/20 0.38
CES1 P23141 6/20 0.38
EGLN1 Q9GZT9 1/20 0.36
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34
CYP2D6 P10635 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP1A2 P05177 1/20 0.34
HDAC4 P56524 2/20 0.33
HDAC6 Q9UBN7 2/20 0.33
TSHR P16473 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14194363 0.85 ACHE (0.44) GLO1ALDH1A1ACHECES2CES1
SCHEMBL24017506 0.85 GLO1 (0.38) GLO1ALDH1A1LMNAHSD17B10ACHE
SCHEMBL14261426 0.81 MAPT (0.37) GLO1ALDH1A1LMNAHSD17B10ACHE
SCHEMBL13871304 0.81 ALDH1A1 (0.50) GLO1ALDH1A1LMNAHSD17B10EGLN1
SCHEMBL20265954 0.79 SOAT1 (0.35) GLO1ALDH1A1LMNAHSD17B10ACHE
SCHEMBL166910 0.79 ALDH1A1 (0.43) GLO1ALDH1A1LMNAHSD17B10ACHE
SCHEMBL3474110 0.78 ALDH1A1 (0.42) GLO1ALDH1A1LMNAHSD17B10ACHE
Water SCHEMBL3826998 0.77 ALDH1A1 (0.43) GLO1ALDH1A1LMNAHSD17B10ACHE
SCHEMBL14194445 0.77 GLO1 (0.50) GLO1ALDH1A1LMNAHSD17B10EGLN1
SCHEMBL20456805 0.77 GLO1 (0.38) GLO1ALDH1A1LMNAHSD17B10ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7364841-B2 Comprising support having thereon light-insensitive organic silver salt grains, photosensitive silver halide grains, a reducing agent for silver ions and a binder; improved storage stability, image lasting quality; use in medical diagnosis and graphic arts KONICA MINOLTA & MEDICAL GRAPHIC, INC. (JP) 2008-04-29 US disclosed
US-7202019-B2 Photothermographic imaging material KONICA MINOLTA HOLDINGS, INC. (JP) 2007-04-10 US disclosed
US-7202019-B2 Photothermographic imaging material KONICA MINOLTA HOLDINGS, INC. (JP) 2007-04-10 US disclosed
US-7175978-B2 Silver salt photothermographic dry imaging material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-02-13 US disclosed
US-20070003886-A1 SILVER SALT PHOTOTHERMOGRAPHIC DRY IMAGING MATERIAL KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-04 US disclosed