Sugi Predict

Sugi Predict / Compounds / SCHEMBL3474110

SCHEMBL3474110

SCHEMBL3474110

CCOC(=O)C(C(=O)OCC)=C(C)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.42
▸ LMNA P02545 1/20 0.42
▸ HSD17B10 Q99714 1/20 0.42
▸ GLO1 Q04760 1/20 0.42
▸ MAPT P10636 1/20 0.38
▸ NPSR1 Q6W5P4 2/20 0.38
▸ ACHE P22303 6/20 0.37
▸ CES2 O00748 5/20 0.37
▸ CES1 P23141 5/20 0.37
▸ TSHR P16473 1/20 0.36
▸ HDAC4 P56524 2/20 0.36
▸ HDAC6 Q9UBN7 2/20 0.36
▸ HDAC3 O15379 1/20 0.36
▸ HDAC1 Q13547 1/20 0.36
▸ ALOX15 P16050 1/20 0.36
▸ MGAM O43451 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ SI P14410 1/20 0.36
▸ MGAM2 Q2M2H8 1/20 0.36
▸ SOAT1 P35610 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14999140 0.92 GLO1 (0.44) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL20456805 0.90 GLO1 (0.38) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL20262497 0.80 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL6317817 0.79 ALOX15 (0.43) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL6317814 0.79 ALOX15 (0.43) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL24017506 0.78 GLO1 (0.38) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL14194366 0.78 GLO1 (0.38) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL24581236 0.78 HPGD (0.33) ALDH1A1LMNAMAPTNPSR1TSHR
SCHEMBL6732281 0.76 GLO1 (0.41) ALDH1A1LMNAHSD17B10GLO1MAPT
SCHEMBL6732284 0.76 GLO1 (0.41) ALDH1A1LMNAHSD17B10GLO1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11186660-B2 Internal electron donor compound for preparing α-olefin polymerization catalyst component YINGKOU XIANGYANG CATALYST CO., LTD. 2021-11-30 — — US claimed
US-20190218317-A1 INTERNAL ELECTRON DONOR COMPOUND FOR PREPARING ALPHA-OLEFIN POLYMERIZATION CATALYST COMPONENT YINGKOU XIANGYANG CATALYST CO LTD (CN) 2019-07-18 — — US claimed
US-10287371-B2 Internal electron donor compound for preparing α-olefin polymerization catalyst component YINGKOU XIANGYANG CATALYST CO., LTD. (CN) 2019-05-14 — — US claimed
CN-103554312-B A kind of internal electron donor compound for preparing alpha-olefin polymerization catalyst component 营口市向阳催化剂有限责任公司 2016-08-17 — — CN claimed
US-20160229935-A1 Internal Electron Donor Compound for Preparing Alpha-olefin Polymerization Catalyst Component DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2016-08-11 — — US claimed
CN-103554312-A Internal electron donor compound for preparing alpha-olefin polymerization catalyst component YINGKOU XIANGYANG CATALYST CO LTD 2014-02-05 — — CN claimed
EP-1042372-B1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE SPA (IT) 2004-07-14 — — EP claimed
CN-1146585-C catalyst component and catalyst for olefin polymerization ض� 2004-04-21 — — CN claimed
US-20030207754-A1 Process for the polymerization of olefins MORINI GIAMPIERO (IT) 2003-11-06 — — US claimed
US-20030207755-A1 Heteroatom containing malonates used in catalysts for the polymerization of olefins MORINI GIAMPIERO (IT) 2003-11-06 — — US claimed
US-20030199388-A1 Catalysts for the polymerization of olefins EQUISTAR CHEMICALS, LP 2003-10-23 — — US claimed
US-6605562-B1 Comprising TiCl4, MgCl2 and an electron donor compound selected from heteroatom containing esters of malonic acids; heteroatoms are preferably selected from F, Cl, Br, and Si BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-08-12 — — US claimed
CN-1292800-A catalyst component and catalyst for olefin polymerization MONTELL TECHNOLOGY COMPANY BV (NL) 2001-04-25 — — CN claimed
EP-1042372-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Montell Technology Company bv (NL) 2000-10-11 — — EP claimed
WO-2000026259-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS MONTELL TECHNOLOGY COMPANY BV (NL) 2000-05-11 — — WO claimed
EP-4692076-A1 HIV INHIBITOR COMPOUNDS Gilead Sciences, Inc. (US) 2026-02-11 — — EP disclosed
US-20260034084-A1 MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF NAVITOR PHARM INC (US) 2026-02-05 — — US disclosed
EP-0372816-B1 NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1992-07-29 — — EP disclosed
WO-1990006304-A1 NOVEL HETEROCYCLIC PESTICIDAL COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1990-06-14 — — WO disclosed
EP-0372816-A1 Novel heterocyclic pesticidal compounds THE WELLCOME FOUNDATION LIMITED (GB) 1990-06-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034084-A1 MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF RICTOR, RPTOR, MTOR ALDH1A1 3529/4885LMNA 3786/4885HSD17B10 1739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.