SCHEMBL166910

SCHEMBL166910

CCOC(=O)C(=O)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
LMNA P02545 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NPSR1 Q6W5P4 2/20 0.41
GLO1 Q04760 1/20 0.41
CES2 O00748 4/20 0.40
ACHE P22303 4/20 0.40
CES1 P23141 4/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
SOAT1 P35610 1/20 0.40
HDAC4 P56524 2/20 0.39
HDAC6 Q9UBN7 2/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
EGLN1 Q9GZT9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL3826998 0.98 ALDH1A1 (0.43) ALDH1A1LMNAHSD17B10NPSR1GLO1
SCHEMBL7046377 0.86 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10NPSR1GLO1
SCHEMBL12918771 0.84 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10NPSR1GLO1
SCHEMBL2133814 0.83 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10NPSR1GLO1
SCHEMBL20907144 0.82 HDAC4 (0.39) ALDH1A1LMNAHSD17B10NPSR1GLO1
SCHEMBL31710040 0.82 CES2 (0.32) ALDH1A1NPSR1GLO1CES2ACHE
SCHEMBL11502313 0.81 ALDH1A1 (0.40) ALDH1A1LMNAHSD17B10NPSR1GLO1
SCHEMBL15109846 0.79 MMP8 (0.42) ALDH1A1LMNAHSD17B10NPSR1GLO1
SCHEMBL24017506 0.79 GLO1 (0.38) ALDH1A1LMNAHSD17B10NPSR1GLO1
Dimethylamine SCHEMBL1406822 0.79 ALDH1A1 (0.42) ALDH1A1LMNAHSD17B10NPSR1GLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 903 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250329799-A1 SYSTEM AND METHOD FOR IMPROVED BATTERY SAFETY Anthro Energy, Inc. (US) 2025-10-23 US claimed
WO-2025091685-A1 FLUORINATED LIQUID COMPOSITION AND USE THEREOF 深圳市鸿富诚新材料股份有限公司 2025-05-08 WO claimed
CN-118515624-B Synthesis method and application of trifluoromethyl-containing polysubstituted oxazolidine-4-one 聊城金歌合成材料有限公司 2025-01-24 CN claimed
CN-118515624-A Synthesis method and application of trifluoromethyl-containing polysubstituted oxazolidine-4-one 聊城金歌合成材料有限公司 2024-08-20 CN claimed
CN-114702460-B Method for synthesizing 2H-1, 3-oxazine compound by utilizing micro-channel reaction device 南京工业大学 2024-05-31 CN claimed
CN-117603661-A Fluorinated liquid composition and application thereof 武汉肯达科讯科技有限公司 2024-02-27 CN claimed
CN-114874418-B Conjugated polymer based on trifluoromethyl substituted quinoxaline, and preparation method and application thereof 广东聚石科技研究有限公司 2023-12-19 CN claimed
CN-114524777-B Synthesis method of dihydro-oxazole compound 南京先进生物材料与过程装备研究院有限公司 2023-10-10 CN claimed
CN-115010641-A Beta-substituted pyrrole derivative, preparation method and application thereof 青岛农业大学 2022-09-06 CN claimed
CN-114874418-A Conjugated polymer based on trifluoromethyl substituted quinoxaline and preparation method and application thereof 广东聚石科技研究有限公司 2022-08-09 CN claimed
CN-114702460-A Method for synthesizing 2H-1, 3-oxazine compound by using microchannel reaction device 南京工业大学 2022-07-05 CN claimed
CN-114524777-A Synthesis method of dihydrooxazole compound 南京先进生物材料与过程装备研究院有限公司 2022-05-24 CN claimed
CN-110878099-B Preparation method of pyrrole [1,2, alpha ] indole alkaloid derivative 五邑大学 2021-11-30 CN claimed
CN-110878099-A Preparation method of pyrrole [1,2, α ] indole alkaloid derivative 五邑大学 2020-03-13 CN claimed
EP-2098501-B1 METHOD FOR PRODUCING OPTICALLY ACTIVE FLUORINE-CONTAINING CARBONYL-ENE PRODUCT CENTRAL GLASS CO LTD (JP) 2017-08-23 EP claimed
US-8278479-B2 Method for producing optically active fluorine-containing carbonyl-ene product CENTRAL GLASS COMPANY, LIMITED (JP) 2012-10-02 US claimed
US-20090312574-A1 Method for Producing Optically Active Fluorine-Containing Carbonyl-ene Product CENTRAL GLASS COMPANY, LIMITED (JP) 2009-12-17 US claimed
EP-2098501-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE FLUORINE-CONTAINING CARBONYL-ENE PRODUCT Central Glass Company, Limited (JP) 2009-09-09 EP claimed
EP-4225762-B1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMA (US) 2026-05-27 EP disclosed
US-4243819-A Substituted amino acids ZOECON CORPORATION (US) 1981-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090312574-A1 Method for Producing Optically Active Fluorine-Containing Carbonyl-ene Product KCNE1, KHK, FOXO1 ALDH1A1 880/4885LMNA 1464/4885HSD17B10 1264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.