Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.38 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PEPD | P12955 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721602 | 0.92 | MAPT (0.41) | PRSS1PRSS2PRSS3F2TMPRSS6 | |
| SCHEMBL1996992 | 0.82 | F2 (0.50) | PRSS1PRSS2PRSS3F2TMPRSS6 | |
| SCHEMBL3117207 | 0.76 | ALDH1A1 (0.60) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL55829 | 0.76 | PEPD (0.58) | ALDH1A1HSD17B10PEPDNPC1KMT2A | |
| SCHEMBL399197 | 0.75 | KIF11 (0.48) | PRSS1PRSS2PRSS3F2TMPRSS6 | |
| Phenylguanidine SCHEMBL256023 | 0.75 | ALDH1A1 (0.58) | PRSS1F2ALDH1A1TP53TYR | |
| SCHEMBL2214384 | 0.74 | ALDH1A1 (0.33) | PRSS1PRSS2PRSS3ALDH1A1TP53 | |
| Phenylguanidine SCHEMBL11092906 | 0.73 | ALDH1A1 (0.56) | PRSS1F2ALDH1A1TP53TYR | |
| SCHEMBL6880468 | 0.73 | F2 (0.43) | PRSS1PRSS2PRSS3F2TMPRSS6 | |
| SCHEMBL1438380 | 0.73 | MAPT (0.56) | PRSS1PRSS2PRSS3F2TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778577-B1 | NOVEL COMPOUND EXHIBITING ENTEROPEPTIDASE INHIBITORY ACTIVITY | LG CHEMICAL LTD (KR) | 2023-08-30 | — | — | EP | claimed |
| CN-105189607-B | Amine-functional polyamides | 建新公司 | 2018-06-15 | — | — | CN | claimed |
| CN-107250189-A | Crosslinking polydiene propylamine copolymer for treating diabetes B | 建新公司 | 2017-10-13 | — | — | CN | claimed |
| CN-106687504-A | Main chain type polyamines | 建新公司 | 2017-05-17 | — | — | CN | claimed |
| CN-105189607-A | Amine-functional polyamides | GENZYME CORP | 2015-12-23 | — | — | CN | claimed |
| CN-105188718-A | Chelants for advanced glycation end product (AGE) precursors | GENZYME CORP | 2015-12-23 | — | — | CN | claimed |
| EP-1797096-B1 | PYRAZOLOPYRIMIDINES AS INHIBITORS OF PROTEIN KINASE B (AKT) | BAYER SCHERING PHARMA AG (DE) | 2011-07-27 | — | — | EP | claimed |
| CN-101027315-B | Method for the synthesis and selective biocatalytic modification of peptides, peptide mimetics and proteins | HOFFMANN LA ROCHE | 2011-05-25 | — | — | CN | claimed |
| CN-101990547-A | Il-23 receptor antagonists and uses thereof | VALORISATION HSJ SOC EN COMMAN | 2011-03-23 | — | — | CN | claimed |
| EP-1534734-B1 | METHOD FOR THE SYNTHESIS AND SELECTIVE BIOCATALYTIC MODIFICATION OF PEPTIDES, PEPTIDE MIMETICS AND PROTEINS | ROCHE DIAGNOSTICS GMBH (DE) | 2008-05-07 | — | — | EP | claimed |
| EP-0024781-B1 | MEDICATED INTRAUTERINE DEVICES | Shaw, Seth Thomas, Jr. (US) | 1984-08-08 | — | — | EP | claimed |
| US-4342869-A | Cephalosporin antibiotics | MERCK & CO., INC. (US) | 1982-08-03 | — | — | US | claimed |
| US-4342757-A | Cephalosporin antibiotic compositions | MERCK & CO., INC. (US) | 1982-08-03 | — | — | US | claimed |
| US-4338437-A | Cephalosporin antibiotics | MERCK & CO., INC. (US) | 1982-07-06 | — | — | US | claimed |
| US-4338438-A | Cephalosporin antibiotics | MERCK & CO., INC. (US) | 1982-07-06 | — | — | US | claimed |
| US-4310459-A | Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters | BRISTOL-MYERS COMPANY (US) | 1982-01-12 | — | — | US | claimed |
| US-4298741-A | DETHIAPENICILLIN ANTIBIOTICS | MERCK & CO., INC. (US) | 1981-11-03 | — | — | US | claimed |
| US-4297488-A | 7-α-Methoxy cephalosporins | MERCK & CO., INC. (US) | 1981-10-27 | — | — | US | claimed |
| US-4258040-A | Cephalosporin compounds | MERCK & CO., INC. (US) | 1981-03-24 | — | — | US | claimed |
| US-4060687-A | Cephalosporins having a 3-α substituted alkyl grouping | MERCK & CO., INC. (US) | 1977-11-29 | — | — | US | claimed |