Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | C1S | P09871 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559153 | 0.81 | L3MBTL1 (0.30) | — | |
| SCHEMBL789578 | 0.80 | GAA (0.50) | ALDH1A1TP53TSHRHSD17B10KMT2A | |
| SCHEMBL27320197 | 0.74 | GAA (0.44) | ALDH1A1HSD17B10KMT2A | |
| SCHEMBL1419477 | 0.74 | PRSS1 (0.38) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL2531539 | 0.73 | EPHX2 (0.41) | TP53TSHRHSD17B10KMT2A | |
| Phenylguanidine SCHEMBL256023 | 0.73 | ALDH1A1 (0.58) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL6973539 | 0.72 | TAS2R38 (0.57) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL50031 | 0.72 | HSD17B10 (0.57) | ALDH1A1TSHRHSD17B10KMT2A | |
| SCHEMBL3111441 | 0.72 | CA1 (0.51) | — | |
| Phenylguanidine SCHEMBL11092906 | 0.72 | ALDH1A1 (0.56) | ALDH1A1TP53TYRTSHRTAS2R38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836613-B1 | WATER-SOLUBLE ADENOSINE KINASE INHIBITORS | METABASIS THERAPEUTICS INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1525195-A2 | METHOD FOR THE PRODUCTION OF PHENYLALANINE DERIVATIVES | Wilex AG (DE) | 2005-04-27 | — | — | EP | claimed |
| WO-2004011449-A2 | METHOD FOR THE PRODUCTION OF PHENYLALANINE DERIVATIVES | WILEX AG (DE) | 2004-02-05 | — | — | WO | claimed |
| EP-1305028-A4 | ANTIMICROBIAL BIARYL COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 2004-01-21 | — | — | EP | claimed |
| EP-1305028-A2 | ANTIMICROBIAL BIARYL COMPOUNDS | ISIS Pharmaceuticals, Inc. (US) | 2003-05-02 | — | — | EP | claimed |
| WO-2002009648-A2 | ANTIMICROBIAL BIARYL COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2002-02-07 | — | — | WO | claimed |
| US-5952307-A | Basic α-aminoalkylphosphonate derivatives | GEORGIA TECH RESEARCH CORP. (US) | 1999-09-14 | — | — | US | claimed |
| US-5795977-A | Water soluble adenosine kinase inhibitors | METABASIS THERAPEUTICS, INC. (US) | 1998-08-18 | — | — | US | claimed |
| EP-0836613-A1 | WATER-SOLUBLE ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-22 | — | — | EP | claimed |
| US-5686419-A | SERINE PROTEASE INHIBITOR ANTICOAGULANTS | GEORGIA TECH RESEARCH CORP. (US) | 1997-11-11 | — | — | US | claimed |
| US-5652237-A | 2-substituted-4H-3, 1-benzoxazin-4-ones and benzthiazin-4-ones as inhibitors of complement C1r protease for the treatment of inflammatory processes | WARNER-LAMBERT COMPANY (US) | 1997-07-29 | — | — | US | claimed |
| WO-1996040707-A1 | WATER-SOLUBLE ADENOSINE KINASE INHIBITORS | GENSIA SICOR (US) | 1996-12-19 | — | — | WO | claimed |
| US-5532255-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-02 | — | — | US | claimed |
| WO-1996007648-A1 | 2-SUBSTITUTED-4H-3,1-BENZOXAZIN-4-ONES AND BENZTHIAZIN-4-ONES AS INHIBITORS OF COMPLEMENT Clr PROTEASE FOR THE TREATMENT OF INFLAMMATORY PROCESSES | WARNER-LAMBERT COMPANY (US) | 1996-03-14 | — | — | WO | claimed |
| EP-0387771-B1 | Benzopyran derivatives | ONO PHARMACEUTICAL CO (JP) | 1995-06-07 | — | — | EP | claimed |
| EP-0325406-B1 | Diamine compounds | ICI PLC (GB) | 1993-12-29 | — | — | EP | claimed |
| EP-0325406-A2 | Diamine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-07-26 | — | — | EP | claimed |
| CN-105377862-A | Metal-based complexes as photodynamic compounds and use thereof | MCFARLAND SHERRI ANN | 2016-03-02 | — | — | CN | disclosed |
| CN-1004351-B | Method for preparing selaginellin related compound with phenylene | 微生物化学研究会 | 1989-05-31 | — | — | CN | disclosed |
| CN-85101425-A | Have Si Baige Eyring allied compound of phenylene and preparation method thereof | — | 1987-01-17 | — | — | CN | disclosed |