P-Xylene

P-Xylene

SCHEMBL1420060

Cc1ccc(C)cc1.c1cnc2c(c1)ccc1ncccc12

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.82
CYP3A4 P08684 2/20 0.56
ALDH1A1 P00352 4/20 0.55
MAPT P10636 5/20 0.52
KDM4E B2RXH2 4/20 0.52
CCR1 P32246 4/20 0.52
CCR8 P51685 4/20 0.52
CCR5 P51681 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
HTT P42858 3/20 0.52
TDP1 Q9NUW8 3/20 0.52
HSP90AA1 P07900 2/20 0.52
GMNN O75496 1/20 0.52
TP53 P04637 1/20 0.52
MMP2 P08253 1/20 0.52
CYP2D6 P10635 1/20 0.52
MMP9 P14780 1/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
NFKB1 P19838 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL3710343 0.93 LMNA (0.77) LMNACYP3A4ALDH1A1MAPTKDM4E
SCHEMBL6513577 0.91 LMNA (1.00) LMNACYP3A4ALDH1A1MAPTKDM4E
SCHEMBL8313 0.91 LMNA (1.00) LMNACYP3A4ALDH1A1MAPTKDM4E
Iodide SCHEMBL10638043 0.89 LMNA (0.96) LMNACYP3A4ALDH1A1MAPTKDM4E
SCHEMBL15788918 0.89 LMNA (0.96) LMNACYP3A4ALDH1A1MAPTKDM4E
SCHEMBL723791 0.89 LMNA (0.96) LMNACYP3A4ALDH1A1MAPTKDM4E
SCHEMBL7722989 0.89 LMNA (0.96) LMNACYP3A4ALDH1A1MAPTKDM4E
SCHEMBL7142651 0.89 LMNA (0.96) LMNACYP3A4ALDH1A1MAPTKDM4E
SCHEMBL3885158 0.89 LMNA (0.96) LMNACYP3A4ALDH1A1MAPTKDM4E
SCHEMBL7268962 0.89 LMNA (0.96) LMNACYP3A4ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2298737-B1 Indole compounds and organic light-emitting device including the same SAMSUNG DISPLAY CO LTD (KR) 2017-05-10 EP disclosed
US-8399880-B2 Heteroarylamine compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2013-03-19 US disclosed
US-8283057-B2 Heteroarylamine compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2012-10-09 US disclosed
EP-2298740-A1 1-H-benzo[g]indole compounds and organic lightemitting device including the same Samsung Mobile Display Co., Ltd. (KR) 2011-03-23 EP disclosed
EP-2298737-A1 Indole compounds and organic light-emitting device including the same Samsung Mobile Display Co., Ltd. (KR) 2011-03-23 EP disclosed
US-20110049484-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-03-03 US disclosed
US-20110049494-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110049494-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME INMT, TYR, HTT LMNA 2664/4885CYP3A4 65/4885ALDH1A1 1062/4885
US-20110049484-A1 HETEROARYLAMINE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME INMT, TYR, HTT LMNA 2664/4885CYP3A4 65/4885ALDH1A1 1062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.