Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003499 | 0.78 | CYP2C19 (0.55) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL3859970 | 0.77 | CYP1A2 (0.33) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL485620 | 0.77 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1MAPTKMT2AL3MBTL1 | |
| SCHEMBL2133730 | 0.74 | CYP2C19 (0.48) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL4901936 | 0.74 | CYP2C19 (0.48) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL18662217 | 0.74 | HRH1 (0.41) | CYP2C19MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL1610252 | 0.72 | CYP2C19 (0.50) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL15816497 | 0.72 | CYP2C19 (0.37) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL4354928 | 0.72 | CYP2C19 (0.46) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL252241 | 0.71 | GABBR2 (0.50) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729195-B2 | Organosilicon compound, method for producing thereof, and curable silicone composition containing the same | DOW CORNING TORAY CO., LTD. (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20120309921-A1 | Organosilicon Compound, Method For Producing Thereof, And Curable Silicone Composition Containing The Same | DOW CORNING TORAY CO., LTD. (JP) | 2012-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309921-A1 | Organosilicon Compound, Method For Producing Thereof, And Curable Silicone Composition Containing The Same | SRM, ESD, THEM6 | CYP2C19 2540/4885SMN1; SMN2 1116/4885ALDH1A1 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.