SCHEMBL14215936

SCHEMBL14215936

O=S(=O)(c1ccccc1Pc1ccccc1)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.33
CA1 P00915 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14215938 0.78 CA2 (0.35) CA2CA1CA5ACA9MEN1
SCHEMBL14215942 0.78 CA2 (0.35) CA2CA1CA5ACA9LMNA
SCHEMBL6929900 0.76 CA2 (0.44) CA2CA1CA5ACA9LMNA
SCHEMBL2593805 0.76 TSHR (0.41) CA2CA1LMNASMN1; SMN2ALDH1A1
SCHEMBL30035563 0.76 TSHR (0.41) CA2CA1LMNASMN1; SMN2ALDH1A1
SCHEMBL14215940 0.76 BCAT2 (0.39) LMNA
SCHEMBL28539965 0.71 DBH (0.39) CA2CA1CA5ACA9MEN1
Trifluoromethanesulfonic Acid SCHEMBL25437843 0.69 GPR3 (0.48) CA2CA1CA5ACA9
SCHEMBL31504077 0.69 HSD11B1 (0.45) CA2KMT2AALDH1A1
SCHEMBL945367 0.69 MEN1 (0.40) CA2CA1CA5ACA9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7378154-B2 Radiation transparent glass, polycarbonate, polyethylene terephthalate, acrylic, methyl cellulose or polycycloolefin substrate, a fluoropolymer layer containing and a rare earth metal compound, and a low refractive index layer; fluorescence; light amplification; improved efficiency; light emitting diodes DAIKIN INDUSTRIES, LTD. (JP) 2008-05-27 US disclosed