SCHEMBL14215940

SCHEMBL14215940

CS(=O)(=O)c1ccccc1Pc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 1/20 0.39
PTGS2 P35354 2/20 0.33
KEAP1 Q14145 1/20 0.33
LOX P28300 1/20 0.33
ACLY P53396 1/20 0.32
DRD2 P14416 1/20 0.32
HSD11B1 P28845 1/20 0.32
HTR6 P50406 3/20 0.32
LMNA P02545 1/20 0.31
CASR P41180 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2593805 0.80 TSHR (0.41) HTR6LMNA
SCHEMBL30035563 0.80 TSHR (0.41) HTR6LMNA
SCHEMBL14215939 0.77 BCAT2 (0.38) BCAT2PTGS2LOXDRD2HSD11B1
SCHEMBL14215936 0.76 CA2 (0.33) LMNA
SCHEMBL288549 0.72 CA1 (0.37) LMNA
SCHEMBL8106699 0.72 LOX (0.47) BCAT2PTGS2KEAP1LOXACLY
SCHEMBL8818051 0.72 TSHR (0.38)
SCHEMBL14215941 0.71 HSD11B1 (0.35) BCAT2LOXACLYDRD2HSD11B1
SCHEMBL8958491 0.71 TSHR (0.36)
SCHEMBL2933394 0.67 TSHR (0.43) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7378154-B2 Radiation transparent glass, polycarbonate, polyethylene terephthalate, acrylic, methyl cellulose or polycycloolefin substrate, a fluoropolymer layer containing and a rare earth metal compound, and a low refractive index layer; fluorescence; light amplification; improved efficiency; light emitting diodes DAIKIN INDUSTRIES, LTD. (JP) 2008-05-27 US disclosed