Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8249373 | 0.88 | DPP4 (0.37) | ALDH1A1POLBDPP4KDM4EGAA | |
| SCHEMBL17399734 | 0.86 | ADRB3 (0.33) | — | |
| SCHEMBL8237366 | 0.85 | DPP4 (0.31) | ALDH1A1DPP4KDM4EGAAALOX15 | |
| SCHEMBL8247123 | 0.84 | DPP4 (0.33) | ALDH1A1DPP4KDM4EGAAALOX15 | |
| SCHEMBL11975940 | 0.81 | HDAC4 (0.33) | ALDH1A1POLBKDM4ETSHRGAA | |
| SCHEMBL8247064 | 0.80 | DPP4 (0.34) | ALDH1A1DPP4KDM4EGAAALOX15 | |
| SCHEMBL13071410 | 0.78 | ALOX15 (0.37) | ALDH1A1DPP4KDM4EGAAALOX15 | |
| SCHEMBL8212674 | 0.77 | ADRB3 (0.34) | — | |
| SCHEMBL8223794 | 0.77 | ADRB3 (0.34) | — | |
| SCHEMBL16938902 | 0.77 | HDAC4 (0.32) | POLBTSHRHDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008057873-A2 | INHIBITORS OF HEPATITIS C VIRUS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-05-15 | — | — | WO | disclosed |