Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12260797 | 0.80 | ENPP2 (0.59) | SLC2A1LTA4HALDH1A1HSD17B1HSD17B2 | |
| SCHEMBL12277315 | 0.80 | ACHE (0.83) | ACHERELALTA4HALDH1A1TEAD4 | |
| SCHEMBL257625 | 0.80 | ACHE (0.83) | ACHERELALTA4HALDH1A1TEAD4 | |
| SCHEMBL13778705 | 0.78 | ALDH1A1 (0.71) | ACHESLC2A1ALDH1A1TSHRHSD17B1 | |
| SCHEMBL10023997 | 0.78 | SLC2A1 (0.67) | SLC2A1LTA4HALDH1A1TSHRMAPT | |
| SCHEMBL12748396 | 0.78 | TEAD4 (0.64) | ACHEALDH1A1TSHRTEAD4AR | |
| SCHEMBL12770829 | 0.77 | ACHE (0.56) | ACHERELALTA4HALDH1A1TEAD4 | |
| SCHEMBL8943781 | 0.77 | ACHE (0.62) | ACHESLC2A1RELALTA4HALDH1A1 | |
| SCHEMBL15474243 | 0.76 | HSD17B1 (0.51) | ACHEALDH1A1TSHRHSD17B1HSD17B2 | |
| SCHEMBL116727 | 0.76 | ALDH1A1 (0.61) | SLC2A1ALDH1A1TSHRMAPTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063300-A2 | BORONIC ACIDS AND ESTERS AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC. (US) | 2008-05-29 | — | — | WO | disclosed |