Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 9/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 9/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 9/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28074789 | 0.88 | SCN4A (0.38) | HPGDSGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL7421479 | 0.83 | GABRG2 (0.40) | HPGDSGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL22190961 | 0.83 | HPGDS (0.39) | HPGDSGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL22263387 | 0.81 | GABRG2 (0.36) | HPGDSGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL6586676 | 0.80 | PTGDR2 (0.34) | HPGDSGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL28677416 | 0.80 | NOS1 (0.51) | NOS1GABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL1414894 | 0.79 | NOS1 (0.51) | NOS1ALDH1A1TSHRKDM4EGAA | |
| SCHEMBL28155365 | 0.79 | BCHE (0.37) | NOS1MAPTHPGDKMT2A | |
| SCHEMBL27610277 | 0.77 | TSHR (0.49) | HPGDSGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL23015484 | 0.75 | ALDH1A1 (0.38) | HPGDSGABRG2GABRB3GABRA5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292499-A | New preparation method of beta-lactamase inhibitor and intermediate thereof | 齐鲁制药有限公司 | 2021-08-24 | — | — | CN | claimed |
| CN-113292499-B | New preparation method of beta-lactamase inhibitor and intermediate thereof | 齐鲁制药有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-114907301-B | Ranitivir octanoate intermediate and preparation method thereof | 上海医药工业研究院 | 2024-05-28 | — | — | CN | disclosed |
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-111116567-B | Zanamivir and ranamivir intermediates and synthesis method thereof | 中国科学院上海有机化学研究所 | 2023-10-10 | — | — | CN | disclosed |
| CN-111116533-B | Zanamivir and ranamivir intermediate and synthesis method thereof | 中国科学院上海有机化学研究所 | 2022-11-22 | — | — | CN | disclosed |
| CN-114907301-A | Ranitivir caprylate intermediate and preparation method thereof | 上海医药工业研究院 | 2022-08-16 | — | — | CN | disclosed |
| CN-113801082-A | Preparation method of lanimivir octanoate | 博瑞生物医药（苏州）股份有限公司 | 2021-12-17 | — | — | CN | disclosed |
| CN-113801138-A | Method for preparing lanimivir octanoate intermediate by one-pot method | 博瑞生物医药（苏州）股份有限公司 | 2021-12-17 | — | — | CN | disclosed |
| CN-111018901-B | Zanamivir and ranamivir intermediate and synthesis method thereof | 中国科学院上海有机化学研究所 | 2021-09-03 | — | — | CN | disclosed |
| CN-1656086-A | Benzofuran derivative | TANABE SEIYAKU CO (JP) | 2005-08-17 | — | — | CN | disclosed |
| CN-1656107-A | Plasma carboxypeptidase B inhibitors | SCHERING AG (DE) | 2005-08-17 | — | — | CN | disclosed |
| WO-2004087138-A1 | METHOD FOR TREATING VASCULAR HYPERPERMEABLE DISEASE | SUCAMPO AG (CH) | 2004-10-14 | — | — | WO | disclosed |
| WO-2004067521-A1 | THIAZOLE DERIVATIVES AND THEIR USE AS VAP-1 INHIBITORS | ASTELLAS PHARMA INC. (JP) | 2004-08-12 | — | — | WO | disclosed |
| EP-1442027-A1 | SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2004-08-04 | — | — | EP | disclosed |
| CN-1439006-A | Novel compounds possessing antibacterial, antifungal or antitumor activity | GENELABS TECH INC (US) | 2003-08-27 | — | — | CN | disclosed |
| WO-2003031419-A1 | SUBSTITUTED DIPHENYLOXAZOLES, THE SYNTHESIS THEREOF, AND THE USE THEREOF AS FLUORESCENCE PROBES | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-04-17 | — | — | WO | disclosed |
| CN-1337961-A | Heteroaryl amidines, methyl amidiues and guanidines as protease inhibitors | DIMENSIONAL PHARM INC (US) | 2002-02-27 | — | — | CN | disclosed |
| CN-1303365-A | Benzamide and sulfonamide substituted aminoguanidines and alkoxyguanidines as protease inhibitors | DIMENSIONAL PHARM INC (US) | 2001-07-11 | — | — | CN | disclosed |
| CN-1237961-A | Aminoguanidines and alkoxyguanidines as protease inhibitors | DIMENSIONAL PHARM INC (US) | 1999-12-08 | — | — | CN | disclosed |