Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17657914 | 0.78 | PTGER4 (0.43) | ALDH1A1MAPTL3MBTL1KDM4EHTT | |
| SCHEMBL29952236 | 0.78 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1HPGDKDM4EHTT | |
| SCHEMBL9095172 | 0.77 | L3MBTL1 (0.51) | ALDH1A1MAPTL3MBTL1HPGDKDM4E | |
| SCHEMBL19214418 | 0.75 | PTGER4 (0.71) | ALDH1A1MAPTL3MBTL1HPGDKDM4E | |
| SCHEMBL11047658 | 0.74 | ALDH1A1 (0.81) | ALDH1A1MAPTL3MBTL1HPGDKDM4E | |
| SCHEMBL7601817 | 0.74 | MEN1 (0.64) | ALDH1A1MAPTL3MBTL1HPGDKDM4E | |
| SCHEMBL14222653 | 0.74 | L3MBTL1 (0.54) | ALDH1A1MAPTL3MBTL1HPGDKDM4E | |
| SCHEMBL4824189 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1HPGDKDM4E | |
| SCHEMBL4824181 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MAPTL3MBTL1HPGDKDM4E | |
| SCHEMBL29957009 | 0.73 | MAPT (0.50) | ALDH1A1MAPTL3MBTL1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008037783-A1 | PROCESS FOR PREPARING 2-OXO-2,5-DIHYDRO-1H-PYRIDO[3,2-B]INDOLE-3-CARBONITRILES | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-04-03 | — | — | WO | disclosed |