Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17657914 | 0.81 | PTGER4 (0.43) | ALDH1A1KDM4EHCRTR1L3MBTL1ATM | |
| SCHEMBL14222649 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL14222653 | 0.76 | L3MBTL1 (0.54) | ALDH1A1KDM4EL3MBTL1ATMHTT | |
| SCHEMBL19485837 | 0.73 | ALDH1A1 (0.53) | ALDH1A1KDM4EMEN1HCRTR1KMT2A | |
| SCHEMBL8140534 | 0.72 | ATM (0.53) | ALDH1A1KDM4EMEN1HCRTR1KMT2A | |
| SCHEMBL4825626 | 0.72 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1HCRTR1KMT2A | |
| SCHEMBL4825621 | 0.72 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1HCRTR1KMT2A | |
| SCHEMBL21978883 | 0.71 | ATM (0.43) | ALDH1A1KDM4EMEN1HCRTR1KMT2A | |
| SCHEMBL21957282 | 0.71 | ATM (0.46) | ALDH1A1KDM4EMEN1HCRTR1KMT2A | |
| SCHEMBL31027366 | 0.71 | ATM (0.46) | ALDH1A1KDM4EMEN1HCRTR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |