Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | MGAM | O43451 | 5/20 | 0.45 |
| ▸ | SI | P14410 | 5/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | COASY | Q13057 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11628987 | 0.98 | ACHE (0.45) | ACHEGRIN1GRIN2BGAAMGAM | |
| SCHEMBL3986301 | 0.79 | ACHE (0.43) | ACHEGRIN1GRIN2BGAAMGAM | |
| SCHEMBL3884588 | 0.79 | PARP1 (0.59) | ACHEGRIN1GRIN2BGAAMGAM | |
| SCHEMBL8956217 | 0.79 | PSMD14 (0.39) | GRIN1GRIN2BGAAMGAMSI | |
| SCHEMBL6139625 | 0.79 | MGAM (0.60) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL14222708 | 0.79 | NUDT1 (0.51) | ACHEGRIN1GRIN2BGAAMGAM | |
| SCHEMBL9305483 | 0.79 | RAB9A (0.50) | ACHEGRIN1GRIN2BGAAMGAM | |
| SCHEMBL9533100 | 0.76 | GRIN1 (0.55) | ACHEGRIN1GRIN2BGAAMGAM | |
| SCHEMBL8731207 | 0.75 | PARP1 (0.35) | GAAMGAMSIMGAM2KDM4E | |
| SCHEMBL56853 | 0.75 | PARP1 (0.62) | GRIN2BGAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | claimed |
| US-4131467-A | 4,7-Dihydroxybenzimidazole hydrobromide as antifogger | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-12-26 | — | — | US | claimed |
| CN-118406235-A | High-temperature-resistant polyarylsulfone resin and preparation method thereof | 吉林大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-114163647-B | Biomass polybenzimidazole epoxy flame-retardant curing agent and preparation method and application thereof | 厦门大学 | 2022-08-12 | — | — | CN | disclosed |
| CN-114163647-A | Biomass polybenzimidazole epoxy flame-retardant curing agent and preparation method and application thereof | 厦门大学 | 2022-03-11 | — | — | CN | disclosed |
| US-7547756-B2 | Benzimidazole-containing sulfonated polyethersulfones | GENERAL ELECTRIC COMPANY (US) | 2009-06-16 | — | — | US | disclosed |
| US-20070100131-A1 | Benzimidazole-containing sulfonated polyethersulfones | GENERAL ELECTRIC COMPANY | 2007-05-03 | — | — | US | disclosed |
| EP-1428510-A1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use | L'OREAL (FR) | 2004-06-16 | — | — | EP | disclosed |
| US-6455507-B1 | E.G., 2-BROMO-5,6-DICHLORO-1-BETA-D-RIBOPYRANOSYL-1H-BENZIMIDAZOLE; VIRICIDES, ESPECIALLY INFECTIONS OF HERPES AND CYTOMEGALO VIRUSES | SMITHKLINE BEECHAM CORPORATION | 2002-09-24 | — | — | US | disclosed |
| US-20020094963-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO WELLCOME INC. | 2002-07-18 | — | — | US | disclosed |
| EP-0994890-A2 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-04-26 | — | — | EP | disclosed |
| WO-1998056761-A2 | BENZIMIDAZOLE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1998-12-17 | — | — | WO | disclosed |
| US-5194433-A | Improved effectiveness against resistant bacteria | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-03-16 | — | — | US | disclosed |
| EP-0287806-B1 | RUBBER COMPOSITIONS MODIFIED WITH HYDROXY-BENZIMIDAZOLE OXIDES | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0485808-A2 | Antibiotic C-3 catechol-substituted cephalosporin compounds, compositions and use thereof | Bristol-Myers Squibb Company (US) | 1992-05-20 | — | — | EP | disclosed |
| EP-0319733-A2 | Process, modified rubbers and rubber compositions | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1989-06-14 | — | — | EP | disclosed |
| EP-0287806-A1 | Rubber compositions modified with hydroxy-benzimidazole oxides | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-10-26 | — | — | EP | disclosed |
| EP-0286851-A1 | Rubber compositions modified with benzimidazolinones | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-10-19 | — | — | EP | disclosed |
| US-4131467-A | 4,7-Dihydroxybenzimidazole hydrobromide as antifogger | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094963-A1 | BENZIMIDAZOLE DERIVATIVES | ZC3HAV1, BRPF3, BRD3 | ACHE 3737/4885GRIN1 2843/4885GRIN2B 2639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.