Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585951 | 0.86 | ALDH1A1 (0.77) | CYP3A4ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL21474106 | 0.85 | ALDH1A1 (0.68) | CYP3A4ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL64766 | 0.85 | ALDH1A1 (0.68) | CYP3A4ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL7877908 | 0.85 | ALDH1A1 (0.68) | CYP3A4ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL15035721 | 0.83 | CYP3A4 (0.58) | CYP3A4ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL14018284 | 0.81 | ALDH1A1 (0.85) | CYP3A4ALDH1A1TDP1TSHRMAPK1 | |
| 4,4'-Methylenedianiline SCHEMBL28001 | 0.80 | CYP3A4 (1.00) | CYP3A4ALDH1A1TDP1TSHRTP53 | |
| SCHEMBL3482770 | 0.80 | CYP3A4 (1.00) | CYP3A4ALDH1A1TDP1TSHRTP53 | |
| SCHEMBL6362775 | 0.80 | CYP3A4 (1.00) | CYP3A4ALDH1A1TDP1TSHRTP53 | |
| SCHEMBL8094139 | 0.80 | CYP3A4 (1.00) | CYP3A4ALDH1A1TDP1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079961-A1 | PHOTOALIGNMENT COMPOSITION | ROLIC AG (CH) | 2018-03-22 | — | — | US | disclosed |
| US-9765235-B2 | Photoaligning material | ROLIC AG (CH) | 2017-09-19 | — | — | US | disclosed |
| US-9366906-B2 | Photoreactive compounds | ROLIC AG (CH) | 2016-06-14 | — | — | US | disclosed |
| US-9097938-B2 | Photoaligning material | ROLIC AG (CH) | 2015-08-04 | — | — | US | disclosed |
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2014-07-10 | — | — | US | disclosed |
| US-20140162076-A1 | PHOTOALIGNING MATERIAL | ROLIC AG (CH) | 2014-06-12 | — | — | US | disclosed |
| US-20130035446-A1 | PHOTOALIGNING MATERIAL | ROLIC AG (CH) | 2013-02-07 | — | — | US | disclosed |
| US-20120316317-A1 | PHOTOALIGNING MATERIAL WITH LATERAL SUBSTITUTION | ROLIC AG (CH) | 2012-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316317-A1 | PHOTOALIGNING MATERIAL WITH LATERAL SUBSTITUTION | LATS1, LATS2, LCP1 | CYP3A4 3964/4885ALDH1A1 4503/4885TDP1 3884/4885 |
| US-20130035446-A1 | PHOTOALIGNING MATERIAL | MAP1LC3C, MAP1LC3A, LCP1 | CYP3A4 4082/4885ALDH1A1 3420/4885TDP1 2355/4885 |
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | PCNA, CRY1, CRY2 | CYP3A4 1905/4885ALDH1A1 2806/4885TDP1 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.