Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829455 | 0.84 | TSHR (0.46) | MAPTALDH1A1LMNAHTTCYP3A4 | |
| SCHEMBL13152525 | 0.76 | VCAM1 (0.39) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL3836060 | 0.76 | TSHR (0.46) | MAPTKDM4EALDH1A1LMNACYP3A4 | |
| SCHEMBL27801408 | 0.69 | MAPT (0.34) | MAPTHTTTSHR | |
| SCHEMBL13613558 | 0.67 | VCAM1 (0.40) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL351791 | 0.66 | VCAM1 (0.50) | MAPTALDH1A1LMNA | |
| SCHEMBL15139324 | 0.65 | ALDH1A1 (0.41) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL13613341 | 0.64 | TSHR (0.37) | MAPTALDH1A1LMNACYP3A4TSHR | |
| SCHEMBL17844001 | 0.64 | SMN1; SMN2 (0.40) | MAPTALDH1A1LMNAHTTTSHR | |
| SCHEMBL3201307 | 0.63 | KMT2A (0.36) | ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119703-B1 | NOVEL INDOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON I B KINASE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-12-12 | — | — | EP | disclosed |