Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3781729 | 0.87 | ALDH1A1 (0.41) | PLA2G2AALDH1A1KDM4EALOX15MAPK1 | |
| SCHEMBL3777623 | 0.79 | PLA2G2A (0.46) | PLA2G2AALDH1A1KDM4EALOX15MAPK1 | |
| SCHEMBL3775770 | 0.78 | PLA2G2A (0.45) | PLA2G2AALDH1A1KDM4EALOX15MAPK1 | |
| SCHEMBL3778130 | 0.77 | TLR7 (0.37) | ALDH1A1KDM4ENPSR1HPGDSMN1; SMN2 | |
| SCHEMBL3771013 | 0.75 | EGLN1 (0.39) | PLA2G2AALDH1A1KDM4ENPSR1LMNA | |
| SCHEMBL3771049 | 0.71 | LMNA (0.39) | PLA2G2AALDH1A1KDM4EALOX15MAPK1 | |
| SCHEMBL27727380 | 0.69 | MAPT (0.41) | ALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL3778397 | 0.68 | VDR (0.40) | ALDH1A1KDM4EALOX15MAPK1L3MBTL1 | |
| SCHEMBL3777108 | 0.68 | ALDH1A1 (0.44) | PLA2G2AALDH1A1KDM4EALOX15MAPK1 | |
| SCHEMBL3772821 | 0.68 | ALDH1A1 (0.40) | PLA2G2AALDH1A1KDM4EALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928457-B1 | QUINOLINES AND THEIR THERAPEUTIC USE | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2012-12-12 | — | — | EP | disclosed |