Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.37 |
| ▸ | CNR2 | P34972 | 17/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14237570 | 0.90 | SMN1; SMN2 (0.37) | CNR1CNR2KMT2A | |
| SCHEMBL14237503 | 0.88 | KCNH2 (0.36) | CNR1CNR2 | |
| SCHEMBL14237484 | 0.87 | KCNH2 (0.35) | CNR1CNR2 | |
| SCHEMBL2538676 | 0.86 | SCD (0.42) | CNR1CNR2KMT2A | |
| SCHEMBL14237704 | 0.85 | KCNH2 (0.36) | KMT2A | |
| SCHEMBL14237370 | 0.85 | NPC1 (0.40) | CNR1CNR2KMT2A | |
| SCHEMBL2544290 | 0.81 | NPBWR1 (0.48) | CNR1CNR2 | |
| SCHEMBL14237295 | 0.75 | GPR119 (0.38) | — | |
| SCHEMBL1550677 | 0.75 | GAA (0.40) | CNR1CNR2KMT2A | |
| SCHEMBL4718944 | 0.74 | HRH1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313395-B1 | PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2012-12-19 | — | — | EP | claimed |