Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | WNT1 | P04628 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14239355 | 0.92 | L3MBTL1 (0.43) | L3MBTL1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL14239053 | 0.89 | L3MBTL1 (0.42) | L3MBTL1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL14239061 | 0.86 | BACE1 (0.40) | L3MBTL1NPC1RAB9A | |
| SCHEMBL14239342 | 0.85 | RAB9A (0.45) | L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6921870 | 0.85 | RAB9A (0.40) | L3MBTL1NPC1RAB9ASMN1; SMN2APOBEC3A | |
| SCHEMBL14239059 | 0.85 | RAB9A (0.35) | L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14239051 | 0.84 | RAB9A (0.40) | L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14238974 | 0.83 | L3MBTL1 (0.39) | L3MBTL1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL14239058 | 0.83 | METAP2 (0.40) | L3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14239811 | 0.83 | RAB9A (0.37) | L3MBTL1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170845-A2 | METABOTROPIC GLUTAMATE RECEPTOR 5 MODULATORS AND METHODS OF USE THEREOF | HEFFERNAN MICHELE L R (US) | 2012-12-13 | — | — | WO | disclosed |