Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1424343 | 0.83 | TDP1 (0.40) | TDP1CYP3A4GABRPGABRDGABRA1 | |
| SCHEMBL1424213 | 0.83 | NQO2 (0.43) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1424280 | 0.83 | TDP1 (0.40) | TDP1CYP3A4ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL16862889 | 0.81 | TDP1 (0.41) | TDP1CYP3A4NOS3NOS2ALDH1A1 | |
| SCHEMBL1424719 | 0.80 | TDP1 (0.40) | TDP1CYP3A4ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1424317 | 0.77 | TDP1 (0.47) | TDP1CYP3A4ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL29390992 | 0.77 | TDP1 (0.50) | TDP1CYP3A4ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL116082 | 0.77 | TDP1 (0.50) | TDP1CYP3A4ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL3218994 | 0.77 | TDP1 (0.50) | TDP1CYP3A4ALDH1A1MAPK1SMN1; SMN2 | |
| Potassium SCHEMBL30575490 | 0.75 | TDP1 (0.48) | TDP1CYP3A4ALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603364-B2 | 4-amino-6-(halo-substituted-alkyl)-picolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2017-03-28 | — | — | US | disclosed |
| US-9603364-B2 | 4-amino-6-(halo-substituted-alkyl)-picolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2017-03-28 | — | — | US | disclosed |
| WO-2015099993-A1 | 4-AMINO-6-(HALO-SUBSTITUTED-ALKYL)-PICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2015-07-02 | — | — | WO | disclosed |
| US-20150164074-A1 | 4-AMINO-6-(HALO-SUBSTITUTED-ALKYL)-PICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2015-06-18 | — | — | US | disclosed |
| US-20150164074-A1 | 4-AMINO-6-(HALO-SUBSTITUTED-ALKYL)-PICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2015-06-18 | — | — | US | disclosed |
| EP-1608624-B1 | 6-ALKYL OR ALKENYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2011-03-23 | — | — | EP | disclosed |
| CN-100519532-C | 6-alkyl-or alkenyl-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2009-07-29 | — | — | CN | disclosed |
| US-7432227-B2 | 6-alkyl or alkenyl-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2008-10-07 | — | — | US | disclosed |
| CN-1764646-A | 6-alkyl-or alkenyl-4-aminopicolinates and their use as herbicides | DOW AGROSCIENCES LLC (US) | 2006-04-26 | — | — | CN | disclosed |
| EP-1608624-A2 | 6-ALKYL OR ALKENYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004089906-A2 | 6-ALKYL OR ALKENYL-4-AMINOPICOLINATES AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2004-10-21 | — | — | WO | disclosed |
| US-20040198608-A1 | 6-Alkyl or alkenyl-4-aminopicolinates and their use as herbicides | CORTEVA AGRISCIENCE LLC | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040198608-A1 | 6-Alkyl or alkenyl-4-aminopicolinates and their use as herbicides | AADAC, AASDHPPT, AADAT | TDP1 3420/4885CYP3A4 525/4885NOS3 3449/4885 |
| US-20150164074-A1 | 4-AMINO-6-(HALO-SUBSTITUTED-ALKYL)-PICOLINATES AND THEIR USE AS HERBICIDES | SLC6A7, HDHD5, DDT | TDP1 2995/4885CYP3A4 591/4885NOS3 4269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.