Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | DRD2 | P14416 | 5/20 | 0.62 |
| ▸ | DRD1 | P21728 | 5/20 | 0.61 |
| ▸ | HTR2C | P28335 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | PTPRCAP | Q14761 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norboldine SCHEMBL29886755 | 0.92 | DRD1 (0.71) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| Norboldine SCHEMBL14367906 | 0.92 | DRD1 (0.71) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| Norboldine SCHEMBL27987614 | 0.92 | DRD1 (0.71) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| Norboldine SCHEMBL29402012 | 0.92 | DRD1 (0.71) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| Laurotetanine SCHEMBL31300083 | 0.91 | DRD2 (0.74) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| Laurotetanine SCHEMBL905065 | 0.91 | DRD2 (0.74) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| Laurotetanine SCHEMBL905125 | 0.91 | DRD2 (0.74) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL30828734 | 0.89 | DRD1 (0.70) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL14259791 | 0.87 | DRD1 (0.71) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL11055620 | 0.85 | ALDH1A1 (0.69) | ALDH1A1HPGDKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | GILEAD SCIENCES, INC. | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076738-A1 | Phosphonate Analogs Of Hiv Integrase Inhibitor Compounds | TYMP, PNP, PIKFYVE | ALDH1A1 2788/4885HPGD 1374/4885KDM4E 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.