Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GALR3 | O60755 | 1/20 | 0.53 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tebufenpyrad SCHEMBL26848 | 0.89 | LMNA (0.59) | LMNARAB9ASMN1; SMN2KMT2AGALR3 | |
| Tebufenpyrad SCHEMBL8407688 | 0.89 | LMNA (0.59) | LMNARAB9ASMN1; SMN2KMT2AGALR3 | |
| SCHEMBL15220664 | 0.83 | LMNA (0.60) | LMNARAB9ASMN1; SMN2KMT2AGALR3 | |
| SCHEMBL19185953 | 0.82 | LMNA (0.54) | LMNARAB9ASMN1; SMN2KMT2AGALR3 | |
| SCHEMBL14262522 | 0.82 | LMNA (0.54) | LMNARAB9ASMN1; SMN2KMT2AGALR3 | |
| SCHEMBL20968014 | 0.82 | LMNA (0.59) | LMNARAB9ASMN1; SMN2KMT2AGALR3 | |
| SCHEMBL11938500 | 0.82 | LMNA (0.59) | LMNARAB9ASMN1; SMN2KMT2AGALR3 | |
| SCHEMBL11938565 | 0.81 | RAB9A (0.48) | LMNARAB9ASMN1; SMN2KMT2AGALR3 | |
| SCHEMBL19185749 | 0.81 | RAB9A (0.48) | LMNARAB9ASMN1; SMN2KMT2AGALR3 | |
| SCHEMBL11938496 | 0.81 | LMNA (0.72) | LMNARAB9ASMN1; SMN2KMT2AGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7344702-B2 | Contrast agents for myocardial perfusion imaging | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2008-03-18 | — | — | US | disclosed |