Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 9/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11938500 | 1.00 | LMNA (0.59) | LMNAL3MBTL1MAPTATMRAB9A | |
| SCHEMBL11938496 | 0.90 | LMNA (0.72) | LMNAL3MBTL1MAPTATMRAB9A | |
| SCHEMBL13557817 | 0.89 | LMNA (0.59) | LMNAL3MBTL1MAPTATMRAB9A | |
| Tebufenpyrad SCHEMBL26848 | 0.88 | LMNA (0.59) | LMNAL3MBTL1MAPTATMRAB9A | |
| Tebufenpyrad SCHEMBL8407688 | 0.88 | LMNA (0.59) | LMNAL3MBTL1MAPTATMRAB9A | |
| SCHEMBL9527642 | 0.83 | LMNA (0.77) | LMNAL3MBTL1MAPTATMRAB9A | |
| SCHEMBL11938556 | 0.82 | LMNA (0.58) | LMNAL3MBTL1MAPTATMRAB9A | |
| SCHEMBL14262507 | 0.82 | LMNA (0.53) | LMNAL3MBTL1MAPTATMRAB9A | |
| SCHEMBL11938501 | 0.81 | LMNA (0.55) | LMNAL3MBTL1MAPTATMRAB9A | |
| SCHEMBL19185758 | 0.81 | LMNA (0.55) | LMNAL3MBTL1MAPTATMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10889550-B2 | Contrast agents for myocardial perfusion imaging | LANTHEUS MEDICAL IMAGING, INC. (US) | 2021-01-12 | — | — | US | disclosed |
| US-20190127333-A1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | LANTHEUS MEDICAL IMAGING, INC. (US) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127333-A1 | CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING | TNNI3, TNNT2, FABP3 | LMNA 3348/4885L3MBTL1 2200/4885MAPT 4043/4885 |
| US-10889550-B2 | Contrast agents for myocardial perfusion imaging | TNNI3, TNNT2, FABP3 | LMNA 3348/4885L3MBTL1 2200/4885MAPT 4043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.