SCHEMBL19185749

SCHEMBL19185749

CCc1nn(C)c(C(=O)NCc2ccc(C(C)(C)C)c(F)c2)c1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RAB9A P51151 7/20 0.48
▸ LMNA P02545 6/20 0.48
▸ SMN1; SMN2 Q16637 5/20 0.48
▸ GALR3 O60755 1/20 0.48
▸ NR2F2 P24468 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ MAPT P10636 5/20 0.44
▸ ATM Q13315 2/20 0.44
▸ L3MBTL1 Q9Y468 2/20 0.44
▸ NPC1 O15118 5/20 0.42
▸ POLB P06746 1/20 0.42
▸ EPHX2 P34913 1/20 0.40
▸ NR1H4 Q96RI1 1/20 0.40
▸ PTGER4 P35408 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.39
▸ NR3C1 P04150 1/20 0.39
▸ CNR1 P21554 2/20 0.39
▸ CNR2 P34972 2/20 0.39
▸ PTGDR2 Q9Y5Y4 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11938565 1.00 RAB9A (0.48) RAB9ALMNASMN1; SMN2GALR3NR2F2
Tebufenpyrad SCHEMBL8407688 0.83 LMNA (0.59) RAB9ALMNASMN1; SMN2GALR3NR2F2
Tebufenpyrad SCHEMBL26848 0.83 LMNA (0.59) RAB9ALMNASMN1; SMN2GALR3NR2F2
SCHEMBL14262507 0.81 LMNA (0.53) RAB9ALMNASMN1; SMN2GALR3NR2F2
SCHEMBL13753796 0.81 RAB9A (0.53) RAB9ALMNASMN1; SMN2GALR3NR2F2
SCHEMBL15220664 0.79 LMNA (0.60) RAB9ALMNASMN1; SMN2GALR3NR2F2
SCHEMBL8853035 0.79 RAB9A (0.47) RAB9ALMNASMN1; SMN2GALR3NR2F2
SCHEMBL9410381 0.78 SMN1; SMN2 (0.41) RAB9ALMNASMN1; SMN2GALR3NR2F2
SCHEMBL8069793 0.77 LMNA (0.56) RAB9ALMNASMN1; SMN2GALR3NR2F2
SCHEMBL10061335 0.76 LMNA (0.57) RAB9ALMNASMN1; SMN2GALR3NR2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210300878-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING LANTHEUS MEDICAL IMAGING, INC. (US) 2021-09-30 — — US disclosed
US-10889550-B2 Contrast agents for myocardial perfusion imaging LANTHEUS MEDICAL IMAGING, INC. (US) 2021-01-12 — — US disclosed
US-20190127333-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING LANTHEUS MEDICAL IMAGING, INC. (US) 2019-05-02 — — US disclosed
US-9718786-B2 Contrast agents for myocardial perfusion imaging LANTHEUS MEDICAL IMAGING, INC. (US) 2017-08-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190127333-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING TNNI3, TNNT2, FABP3 RAB9A 3276/4885LMNA 3348/4885SMN1; SMN2 2969/4885
US-20210300878-A1 CONTRAST AGENTS FOR MYOCARDIAL PERFUSION IMAGING TNNI3, TNNT2, FABP3 RAB9A 3276/4885LMNA 3348/4885SMN1; SMN2 2969/4885
US-10889550-B2 Contrast agents for myocardial perfusion imaging TNNI3, TNNT2, FABP3 RAB9A 3276/4885LMNA 3348/4885SMN1; SMN2 2969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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