Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953979 | 0.88 | S1PR1 (0.47) | KDM4ESCN9AALDH1A1MAPTMEN1 | |
| SCHEMBL1489132 | 0.84 | RXRA (0.53) | KDM4EALDH1A1MRGPRX4RXRARXRB | |
| SCHEMBL13580696 | 0.79 | SIRT1 (0.50) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL404257 | 0.79 | MRGPRX4 (0.41) | KDM4ESCN9AALDH1A1MAPTMEN1 | |
| SCHEMBL23865023 | 0.75 | RECQL (0.40) | KDM4EALDH1A1HPGDMAPTMEN1 | |
| SCHEMBL3541117 | 0.73 | PDK2 (0.40) | KDM4ESCN9AALDH1A1HPGDRXRA | |
| SCHEMBL3541113 | 0.73 | PDK2 (0.40) | KDM4ESCN9AALDH1A1HPGDRXRA | |
| SCHEMBL13407792 | 0.71 | TAS1R3 (0.59) | RXRA | |
| SCHEMBL21055125 | 0.71 | P4HB (0.46) | HPGDMAPTMEN1HTTKMT2A | |
| SCHEMBL13870617 | 0.71 | ADCY8 (0.50) | ALDH1A1HPGDMAPTMEN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070866-A1 | Chemical compounds | PRAECIS PHARMACEUTICALS INCORPORATED (US) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070866-A1 | Chemical compounds | S1PR1, S1PR2, S1PR5 | KDM4E 1279/4885SCN9A 3292/4885ALDH1A1 1459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.