Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TERT | O14746 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2928938 | 0.87 | ALDH1A1 (0.43) | KDM4ENPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL28817526 | 0.81 | KDM4A (0.49) | KDM4ENPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL29620208 | 0.81 | RAB9A (0.67) | KDM4ENPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL9588524 | 0.81 | RAB9A (0.67) | KDM4ENPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL1898847 | 0.81 | RAB9A (0.67) | KDM4ENPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL153132 | 0.79 | HDAC8 (0.55) | KDM4ENPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL29838155 | 0.79 | HDAC8 (0.55) | KDM4ENPC1RAB9AKMT2ASMN1; SMN2 | |
| Iodide SCHEMBL10938374 | 0.78 | KDM4E (0.54) | KDM4ENPC1RAB9AKMT2ASMN1; SMN2 | |
| Bromide SCHEMBL29396763 | 0.78 | HDAC8 (0.53) | KDM4ENPC1RAB9AKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1171580 | 0.78 | HDAC8 (0.53) | KDM4ENPC1RAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358343-B1 | METHOD FOR DECOLOURING KERATINOUS FIBRES | HENKEL AG & CO KGAA (DE) | 2016-10-19 | — | — | EP | claimed |
| US-8268015-B2 | Method for decolorizing keratin-containing fibers | HENKEL AG & CO. KGAA (DE) | 2012-09-18 | — | — | US | claimed |
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | claimed |
| US-20110247644-A1 | Method for Decolorizing Keratin-Containing Fibers | HENKEL AG & CO. KGAA (DE) | 2011-10-13 | — | — | US | claimed |
| EP-2358343-A2 | METHOD FOR DECOLOURING KERATINOUS FIBRES | Henkel AG & Co. KGaA (DE) | 2011-08-24 | — | — | EP | claimed |
| WO-2010072512-A2 | METHOD FOR DECOLOURING KERATINOUS FIBRES | HENKEL AG & CO. KGAA (DE) | 2010-07-01 | — | — | WO | claimed |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | HENKEL AG & CO. KGAA (DE) | 2010-02-18 | — | — | US | claimed |
| EP-2054012-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | Henkel AG & Co. KGaA (DE) | 2009-05-06 | — | — | EP | claimed |
| WO-2009027237-A2 | KIT FOR THE PROVISION OF COLORANTS | HENKEL AG & CO. KGAA (DE) | 2009-03-05 | — | — | WO | claimed |
| EP-2014275-A2 | Kit for preparing storage-stable formulations | Henkel AG & Co. KGaA (DE) | 2009-01-14 | — | — | EP | claimed |
| WO-2003030845-A1 | AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| WO-2003030847-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| WO-2003030842-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| WO-2003030841-A1 | METHOD FOR DYEING KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-1200050-A2 | DYEING AGENT FOR KERATINOUS FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-05-02 | — | — | EP | claimed |
| US-6371993-B1 | HAIR DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-04-16 | — | — | US | claimed |
| WO-2001010379-A2 | DYEING AGENT FOR KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-02-15 | — | — | WO | claimed |
| EP-1037586-A1 | UTILIZATION OF ONIUM ALDEHYDES AND ONIUM KETONES FOR DYING FIBERS CONTAINING KERATIN | Henkel Kommanditgesellschaft auf Aktien (DE) | 2000-09-27 | — | — | EP | claimed |
| WO-1999018916-A2 | UTILIZATION OF ONIUM ALDEHYDES AND ONIUM KETONES FOR DYING FIBERS CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1999-04-22 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110247644-A1 | Method for Decolorizing Keratin-Containing Fibers | KRT18, PLOD3, DSG1 | KDM4E 508/4885NPC1 4634/4885RAB9A 4093/4885 |
| US-20100037909-A1 | SUBSTANCES FOR DYEING KERATINOUS FIBERS | KRT18, H1-10, COL1A1 | KDM4E 1659/4885NPC1 2664/4885RAB9A 1786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.