Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352519 | 0.81 | PNP (0.43) | PNPALDH1A1LMNACYP1A2CYP2C19 | |
| SCHEMBL523465 | 0.77 | XDH (0.47) | PNPALDH1A1LMNACYP3A4TSHR | |
| SCHEMBL27773184 | 0.77 | ADORA2A (0.43) | — | |
| SCHEMBL4456036 | 0.76 | FDPS (0.34) | FDPSMKNK2ALDH1A1LMNACYP1A2 | |
| SCHEMBL2120550 | 0.75 | FDPS (0.45) | FDPSMKNK2ALDH1A1LMNACYP1A2 | |
| SCHEMBL28340215 | 0.74 | FDPS (0.44) | FDPSMKNK2ALDH1A1LMNACYP1A2 | |
| SCHEMBL6839512 | 0.73 | CYP3A4 (0.34) | FDPSMKNK2ALDH1A1LMNACYP1A2 | |
| SCHEMBL2200951 | 0.73 | PNP (0.36) | PNP | |
| SCHEMBL72147 | 0.72 | XDH (0.50) | PNPALDH1A1LMNACYP3A4TSHR | |
| SCHEMBL8159669 | 0.69 | TDP1 (0.39) | PNPALDH1A1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110974842-B | Methods of identifying compounds for treating cancer | 卡洛斯三世癌症研究中心全国基金会 | 2023-09-19 | — | — | CN | disclosed |
| CN-115337311-A | A composition for treating respiratory system diseases and its preparation method | 南京恒道医药科技股份有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-113916948-A | Based on nanometer CeO2Electrochemical sensor for detecting xanthine and preparation method and application thereof | 哈尔滨商业大学 | 2022-01-11 | — | — | CN | disclosed |
| CN-112638475-A | MicroRNA targeting agents for the treatment of cardiac diseases | 英国研究与创新基金会 | 2021-04-09 | — | — | CN | disclosed |
| CN-110974842-A | Methods of identifying compounds for treating cancer | 卡洛斯三世癌症研究中心全国基金会 | 2020-04-10 | — | — | CN | disclosed |
| CN-104857016-B | Methods of identifying compounds for treating cancer | 卡洛斯三世癌症研究中心全国基金会 | 2019-12-24 | — | — | CN | disclosed |
| WO-2019155969-A1 | NUCLEOSIDASE AGENT HAVING REDUCED CONTAMINANT ACTIVITY | 天野エンザイム株式会社 | 2019-08-15 | — | — | WO | disclosed |
| WO-2012150866-A1 | PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF | INDUSTRIAL RESEARCH LIMITED (NZ) | 2012-11-08 | — | — | WO | disclosed |
| EP-0823252-B2 | Hair conditioning solid | VEDA CORP A (US) | 2011-03-23 | — | — | EP | disclosed |
| US-7794936-B1 | Using thymidine analogs to improve replication in an expanded genetic alphabet | BENNER STEVEN ALBERT | 2010-09-14 | — | — | US | disclosed |