Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037922 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2A | |
| SCHEMBL28147771 | 0.79 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8820865 | 0.77 | ADORA2A (0.46) | — | |
| SCHEMBL11439072 | 0.77 | FDPS (0.36) | FDPSHDAC6 | |
| SCHEMBL3688477 | 0.77 | KDM4E (0.30) | ALDH1A1 | |
| SCHEMBL1426626 | 0.76 | FDPS (0.34) | FDPSMKNK2ALDH1A1LMNACYP1A2 | |
| SCHEMBL2120550 | 0.75 | FDPS (0.45) | FDPSMKNK2ALDH1A1LMNACYP1A2 | |
| SCHEMBL28340215 | 0.74 | FDPS (0.44) | FDPSMKNK2ALDH1A1LMNACYP1A2 | |
| SCHEMBL7197886 | 0.70 | CDK1 (0.41) | — | |
| SCHEMBL38407 | 0.69 | XDH (0.47) | ALDH1A1LMNACYP3A4TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090226439-A1 | METHOD FOR TREATING DEMENTIA OR ALZHEIMER'S DISEASE | GENENTECH, INC. (US) | 2009-09-10 | — | — | US | claimed |
| CN-101203242-A | Methods of treating dementia or Alzheimer's disease with CD20 antibodies | GENENTECH INC (US) | 2008-06-18 | — | — | CN | claimed |
| EP-1874350-A2 | METHOD FOR TREATING DEMENTIA OR ALZHEIMER'S DISEASE WITH A CD20 ANTIBODY | Genentech, Inc. (US) | 2008-01-09 | — | — | EP | claimed |
| WO-2006116369-A2 | METHOD FOR TREATING DEMENTIA OR ALZHEIMER'S DISEASE WITH A CD20 ANTIBODY | GENENTECH, INC. (US) | 2006-11-02 | — | — | WO | claimed |
| US-20060240007-A1 | Method for treating dementia or Alzheimer's disease | GENENTECH, INC. | 2006-10-26 | — | — | US | claimed |
| EP-4351661-A1 | RECOMBINANT ADENO-ASSOCIATED VIRUSES FOR LESCH-NYHAN DISORDERS AND USES THEREOF | The Trustees of The University of Pennsylvania (US) | 2024-04-17 | — | — | EP | disclosed |
| CN-115869342-A | Flammulina velutipes extract, preparation method and application thereof | 百岳特生物技术（上海）有限公司 | 2023-03-31 | — | — | CN | disclosed |
| WO-2022261187-A1 | RECOMBINANT ADENO-ASSOCIATED VIRUSES FOR LESCH-NYHAN DISORDERS AND USES THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2022-12-15 | — | — | WO | disclosed |
| CN-114796392-A | Traditional Chinese medicine composition for treating gout and application thereof | 谷医堂(湖南)健康科技有限公司 | 2022-07-29 | — | — | CN | disclosed |
| US-20220133818-A1 | METHOD AND COMPOSITION FOR TREATING GASTROINTESTINAL INFLAMMATORY DISORDERS | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2022-05-05 | — | — | US | disclosed |
| EP-3930735-A1 | METHOD AND COMPOSITION FOR TREATING GASTROINTESTINAL INFLAMMATORY DISORDERS | The Regents of the University of Colorado, a body corporate (US) | 2022-01-05 | — | — | EP | disclosed |
| CN-111135200-A | Application of flammulina velutipes extract in increasing gene expression amount and/or inhibiting fat accumulation | 百岳特生物技术（上海）有限公司 | 2020-05-12 | — | — | CN | disclosed |
| US-5750729-A | REACTING PROTECTED PYRAN DERIVATIVES TO FORM NUCLEOTIDES | GILEAD SCIENCES,INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5693771-A | REACTING PROTECTED PYRAN COMPOUND WITH PHOSPHITE AND HETEROCYCLIC BASE | GILEAD SCIENCES, INC. (US) | 1997-12-02 | — | — | US | disclosed |
| EP-0807118-A2 | NOVEL COMPOUNDS AND METHODS FOR MAKING AND USING SAME | GILEAD SCIENCES, INC. (US) | 1997-11-19 | — | — | EP | disclosed |
| US-5659023-A | HETEROCYCLIC FURANOSYL OR PYRANOSYL PHOSPHONATE; IMMUNOGENS, OLIGONUCLEOTIDES, ANTIINFECTIVES, ANTIINFLAMMATORY AGENTS | GILEAD SCIENCES, INC. (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0772440-A1 | CARBON MONOXIDE DEPENDENT GUANYLYL CYCLASE MODIFIERS | GLASKY, Alvin J. (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996023801-A2 | NOVEL COMPOUNDS AND METHODS FOR MAKING AND USING SAME | GILEAD SCIENCES, INC. (US) | 1996-08-08 | — | — | WO | disclosed |
| WO-1996003125-A1 | CARBON MONOXIDE DEPENDENT GUANYLYL CYCLASE MODIFIERS | GLASKY ALVIN J (US) | 1996-02-08 | — | — | WO | disclosed |
| US-5447939-A | Purine derivatives used for long term modification of neural activity in mammals, for treatment of mammalian neurological diseases, and for inducing long term changes in membrane potential of mammalian neuron | SPECTRUM PHARMACEUTICALS, INC. | 1995-09-05 | — | — | US | disclosed |