Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15672423 | 0.75 | TDP1 (0.36) | MEN1KMT2ASMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL15318098 | 0.75 | TLR7 (0.34) | — | |
| SCHEMBL12606025 | 0.74 | ESR2 (0.35) | MEN1KMT2A | |
| SCHEMBL16674126 | 0.73 | HSP90AA1 (0.38) | MEN1KMT2ATDP1HDAC6HSP90AA1 | |
| SCHEMBL20647844 | 0.71 | — | — | |
| SCHEMBL14268588 | 0.70 | TDP1 (0.38) | MEN1KMT2ASMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL12216725 | 0.67 | MEN1 (0.55) | MEN1KMT2ASMN1; SMN2L3MBTL1TDP1 | |
| Hydrochloric Acid SCHEMBL29349953 | 0.66 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2TDP1 | |
| Hydrochloric Acid SCHEMBL16593584 | 0.66 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL15177503 | 0.66 | SMN1; SMN2 (0.39) | MEN1KMT2ASMN1; SMN2L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9028880-B2 | Silica nanoparticle agent conjugates | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-05-12 | — | — | US | disclosed |
| US-20130274226-A1 | SILICA NANOPARTICLE AGENT CONJUGATES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2013-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274226-A1 | SILICA NANOPARTICLE AGENT CONJUGATES | TST, NCL, MSN | MEN1 3680/4885KMT2A 1071/4885SMN1; SMN2 3254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.