Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207699 | 0.91 | PLA2G2A (0.47) | LTB4RPLA2G2ACYP4F2CYP4A11CYSLTR2 | |
| SCHEMBL9210323 | 0.82 | LTB4R (0.49) | LTB4RPLA2G2AMAOB | |
| SCHEMBL14272573 | 0.80 | CCR2 (0.47) | LTB4RPLA2G2ACYSLTR1 | |
| SCHEMBL27467039 | 0.78 | MAPT (0.41) | PLA2G2AMAOBCYSLTR2CYSLTR1 | |
| SCHEMBL9950289 | 0.78 | CYSLTR1 (0.54) | CYSLTR2CYSLTR1 | |
| SCHEMBL9950291 | 0.78 | CYSLTR1 (0.54) | CYSLTR2CYSLTR1 | |
| SCHEMBL1167517 | 0.76 | ERCC5 (0.58) | — | |
| SCHEMBL9202908 | 0.75 | PLA2G2A (0.45) | LTB4RPLA2G2ACYP4F2CYP4A11CYSLTR2 | |
| SCHEMBL9202903 | 0.75 | PLA2G2A (0.45) | LTB4RPLA2G2ACYP4F2CYP4A11CYSLTR2 | |
| SCHEMBL27467040 | 0.74 | PLA2G2A (0.41) | PLA2G2ACYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035379-A2 | PROCESS FOR AND INTERMEDIATES OF LEUKOTRIENE ANTAGONISTS | APTUIT LAURUS PRIVATE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |