Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14279166 | 0.82 | KDM1A (0.56) | — | |
| SCHEMBL14279165 | 0.80 | HPGD (0.51) | HPGDTSHRSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2234130 | 0.77 | HPGD (1.00) | HPGDSMN1; SMN2LMNAALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL28152221 | 0.76 | HPGD (0.97) | HPGDSMN1; SMN2LMNAALDH1A1RAB9A | |
| SCHEMBL2330371 | 0.74 | CTRB1 (0.51) | HPGD | |
| SCHEMBL2330374 | 0.74 | CTRB1 (0.51) | HPGD | |
| SCHEMBL2330376 | 0.74 | CTRB1 (0.51) | HPGD | |
| SCHEMBL14279164 | 0.74 | KMT2A (0.54) | HPGDSMN1; SMN2LMNAMAPK14ALDH1A1 | |
| SCHEMBL14279162 | 0.74 | L3MBTL1 (0.53) | SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL5530643 | 0.74 | CTSL (0.70) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320755-B2 | Method of preparing ligands for hydrophobic interaction chromatography | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2008-01-22 | — | — | US | disclosed |
| US-7320755-B2 | Method of preparing ligands for hydrophobic interaction chromatography | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2008-01-22 | — | — | US | disclosed |