Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | CTSV | O60911 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14279166 | 0.88 | KDM1A (0.56) | KMT2ACTSLCTSS | |
| SCHEMBL1161997 | 0.79 | NAMPT (0.75) | KMT2ANAMPTHTTUSP2KEAP1 | |
| SCHEMBL3584207 | 0.78 | CTSB (0.53) | CTSVCTSLCTSBCTSSMAPK14 | |
| SCHEMBL7349361 | 0.78 | CTRB1 (0.56) | KMT2ACTSLCTSSALDH1A1 | |
| SCHEMBL13159683 | 0.76 | HDAC1 (0.64) | LMNAMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13183097 | 0.76 | HDAC1 (0.64) | LMNAMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10801513 | 0.76 | KMT2A (0.65) | KMT2APKMECE1HTTUSP2 | |
| SCHEMBL10659411 | 0.75 | GPR132 (0.72) | ECE1CTSVCTSLCTSBCTSS | |
| SCHEMBL14279165 | 0.75 | HPGD (0.51) | KMT2ALMNANPSR1HPGDSMN1; SMN2 | |
| SCHEMBL202770 | 0.75 | CTSL (0.60) | KMT2AECE1CTSVCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320755-B2 | Method of preparing ligands for hydrophobic interaction chromatography | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2008-01-22 | — | — | US | disclosed |
| US-7320755-B2 | Method of preparing ligands for hydrophobic interaction chromatography | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2008-01-22 | — | — | US | disclosed |