SCHEMBL14280610

SCHEMBL14280610

COCCOc1cc(CI)c(CI)c(CI)c1

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.32
CHRNA4 P43681 1/20 0.32
MAPT P10636 1/20 0.32
MAOA P21397 1/20 0.31
DYRK1A Q13627 1/20 0.31
KDM4E B2RXH2 1/20 0.30
RECQL P46063 1/20 0.30
CHEK2 O96017 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14280635 0.90 PRSS1 (0.30)
SCHEMBL14280599 0.76 KDM4E (0.34) CHRNB2CHRNA4MAOADYRK1AKDM4E
SCHEMBL14280600 0.72 KDM4E (0.39) CHRNB2CHRNA4MAOADYRK1AKDM4E
SCHEMBL25868374 0.71 L3MBTL1 (0.35) CHRNB2CHRNA4MAOADYRK1AKDM4E
SCHEMBL4168797 0.70 ALDH1A1 (0.55) KDM4ERECQL
SCHEMBL19399855 0.69 MEN1 (0.45) MAPTMAOADYRK1AKDM4E
SCHEMBL3440051 0.69 MEN1 (0.49) MAPTMAOADYRK1AKDM4E
SCHEMBL14280603 0.68 ACACB (0.42) MAPTKDM4ERECQL
SCHEMBL19384236 0.67 KDM4E (0.38) MAOADYRK1AKDM4ERECQL
SCHEMBL9706645 0.67 MAPT (0.59) CHRNB2CHRNA4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080021185-A1 initiator systems; block polymers of vinyl acetate, vinyl alcohol, or polyvinyl butyral; use as water-soluble films, biodegradable and water-soluble polymers, detergents, in adhesives and as emulsifier; e.g. star polyethylene glycol modified with polyvinyl alcohol groups through a phenylene spacer CELANESE VENTURES GMBH (DE) 2008-01-24 US disclosed