Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280782 | 0.91 | CYP1A2 (0.36) | SIGMAR1CYP1A2SMN1; SMN2LMNAMAPT | |
| SCHEMBL5144787 | 0.88 | SIGMAR1 (0.45) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5144785 | 0.88 | SIGMAR1 (0.45) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7145153 | 0.86 | SIGMAR1 (0.44) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5588333 | 0.86 | SIGMAR1 (0.44) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Bromide SCHEMBL28770855 | 0.85 | SIGMAR1 (0.43) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL7175041 | 0.85 | PAX8 (0.35) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL453477 | 0.85 | HSP90AA1 (0.36) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL453478 | 0.85 | HSP90AA1 (0.36) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4527151 | 0.84 | CYP1A2 (0.33) | SIGMAR1CYP1A2SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |
| US-20080021180-A1 | CHROMIUM CATALYSTS ACTIVE IN OLEFIN POLYMERIZATION | REPSOL QUIMICA, S.A. | 2008-01-24 | — | — | US | disclosed |