Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4527146 | 1.00 | CYP1A2 (0.33) | CYP1A2TSHRGABRA1GABRB2MEN1 | |
| SCHEMBL14280782 | 0.92 | CYP1A2 (0.36) | CYP1A2GABRA1GABRB2MEN1KMT2A | |
| SCHEMBL23563255 | 0.91 | SIGMAR1 (0.33) | CYP1A2TSHRMEN1KMT2ARAB9A | |
| SCHEMBL1120701 | 0.91 | KMT2A (0.33) | MEN1KMT2ARAB9ALMNA | |
| SCHEMBL1120699 | 0.91 | KMT2A (0.33) | MEN1KMT2ARAB9ALMNA | |
| SCHEMBL29558324 | 0.91 | KMT2A (0.33) | MEN1KMT2ARAB9ALMNA | |
| SCHEMBL9952467 | 0.90 | KMT2A (0.33) | MEN1KMT2ARAB9ALMNA | |
| SCHEMBL16654076 | 0.90 | KMT2A (0.33) | MEN1KMT2ARAB9ALMNA | |
| SCHEMBL4531342 | 0.90 | KMT2A (0.33) | MEN1KMT2ARAB9ALMNA | |
| SCHEMBL4531344 | 0.90 | KMT2A (0.33) | MEN1KMT2ARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971577-B1 | Process for the preparation of unsymmetric bis(imino) compounds | BASELL POLYOLEFINE GMBH (DE) | 2014-11-26 | — | — | EP | disclosed |
| US-8252875-B2 | Process for the preparation of unsymmetric bis(imino) compounds | BASELL POLYOLEFINE GMBH (DE) | 2012-08-28 | — | — | US | disclosed |
| US-20090054609-A1 | Process for the Preparation of Unsymmetric Bis(Imino) Compounds | BASELL POLYOLEFINE GMBH (DE) | 2009-02-26 | — | — | US | disclosed |
| EP-1971577-A2 | PROCESS FOR THE PREPARATION OF UNSYMMETRIC BIS(IMINO) COMPOUNDS | Basell Polyolefine GmbH (DE) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007080081-A2 | PROCESS FOR THE PREPARATION OF UNSYMMETRIC BIS(IMINO) COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054609-A1 | Process for the Preparation of Unsymmetric Bis(Imino) Compounds | FHIT, OAT, NONO | CYP1A2 521/4885TSHR 3481/4885GABRA1 2764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.