Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144785 | 1.00 | SIGMAR1 (0.45) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7145153 | 0.98 | SIGMAR1 (0.44) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5588333 | 0.98 | SIGMAR1 (0.44) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| Bromide SCHEMBL28770855 | 0.97 | SIGMAR1 (0.43) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL21113707 | 0.94 | SIGMAR1 (0.41) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24109066 | 0.89 | SIGMAR1 (0.38) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14280780 | 0.88 | SIGMAR1 (0.38) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4890948 | 0.87 | CYP1A2 (0.37) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL18543904 | 0.87 | CYP3A4 (0.37) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22298164 | 0.85 | KDM4E (0.54) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151188-A1 | GREEN SYNTHESIS METHOD OF ANTIVIRAL DRUG INTERMEDIATE | 上海皓元医药股份有限公司 | 2023-08-17 | — | — | WO | disclosed |
| US-7297806-B2 | Ethylene oligomerization catalyst comprising an iron complex of a 2,6-bis(1-(phenylimino)ethyl)pyridine ligand of given formula with a Lewis acid such as methylalumoxane; forms alpha-olefins of formula H-(CH2-CH2)q-CH=CH2 q=1-18 | EI DU PONT DE NEMOURS AND COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| US-7247687-B2 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-07-24 | — | — | US | disclosed |
| US-7179871-B2 | Non-symmetrical ligands and catalyst systems thereof for ethylene oligomerization to linear alpha olefins | SHELL OIL COMPANY (US) | 2007-02-20 | — | — | US | disclosed |
| EP-1521758-B1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | EP | disclosed |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-03-02 | — | — | US | disclosed |
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | disclosed |
| EP-1294482-B1 | LIGANDS AND CATALYST SYSTEMS THEREOF FOR ETHYLENE OLIGOMERISATION TO LINEAR ALPHA OLEFINS | SHELL INT RESEARCH (NL) | 2005-03-30 | — | — | EP | disclosed |
| US-6740715-B2 | CONTACTING ETHYLENE WITH AN IRON COMPLEX OF A SELECTED 2,6-PYRIDINEDICARBOXALDEHYDE BISIMINE; PRODUCTS MAY BE POLYMERIZED OR CONVERTED INTO AN ALCOHOL | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-05-25 | — | — | US | disclosed |
| US-6710006-B2 | BIS-ARYLIMINEPYRIDINE IRON/COBALT COMPLEXES AS SELECTIVE CATALYSTS IN ETHYLENE OLIGOMERIZATION | SHELL OIL COMPANY | 2004-03-23 | — | — | US | disclosed |
| US-20030144514-A1 | Non-symmetrical ligands and catalyst systems thereof for ethylene oligomerisation to linear alpha olefins | DE BOER ERIC JOHANNES MARIA (NL) | 2003-07-31 | — | — | US | disclosed |
| US-20030050494-A1 | Manufacture of alpha-olefins | BROOKHART MAURICE S (US) | 2003-03-13 | — | — | US | disclosed |
| US-20030036615-A1 | Manufacture of alpha-olefins | BROOKHART MAURICE S (US) | 2003-02-20 | — | — | US | disclosed |
| EP-0994831-B1 | MANUFACTURE OF ALPHA-OLEFINS | DU PONT (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6489497-B1 | SELECTED 2,6-PYRIDINEDICARBOXALDEHYDE BISIMINES USEFUL AS TRIDENTATE LIGANDS FOR ETHYLENE OLIGOMERIZATION CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-12-03 | — | — | US | disclosed |
| US-20020028941-A1 | Ligands and catalyst systems thereof for ethylene oligomerisation to linear alpha olefins | SHELL OIL COMPANY | 2002-03-07 | — | — | US | disclosed |
| US-20020016425-A1 | Non-symmetrical ligands and catalyst systems thereof for ethylene oligomerisation to linear alpha olefins | SHELL OIL COMPANY | 2002-02-07 | — | — | US | disclosed |
| US-6103946-A | BY CONTACTING ETHYLENE WITH AN IRON COMPLEX OF A SELECTED 2,6-PYRIDINEDICARBOXALDEHYDE BISIMINE OR A SELECTED 2,6-DIACYLPYRIDINE BISIMINE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0994831-A1 | MANUFACTURE OF ALPHA-OLEFINS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999002472-A1 | MANUFACTURE OF ALPHA-OLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | MLX, LOX, LMTK3 | SIGMAR1 1143/4885GRIN2D 1282/4885GRIN3B 1118/4885 |
| US-20030050494-A1 | Manufacture of alpha-olefins | ALOX12, ALOX15B, AP1M1 | SIGMAR1 1623/4885GRIN2D 1301/4885GRIN3B 1923/4885 |
| US-20030144514-A1 | Non-symmetrical ligands and catalyst systems thereof for ethylene oligomerisation to linear alpha olefins | OPRM1, AP1M1, OPRD1 | SIGMAR1 21/4885GRIN2D 1089/4885GRIN3B 2239/4885 |
| US-20020028941-A1 | Ligands and catalyst systems thereof for ethylene oligomerisation to linear alpha olefins | OPRM1, OPRD1, PYM1 | SIGMAR1 37/4885GRIN2D 1217/4885GRIN3B 2149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.