Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14221370 | 0.85 | ALDH1A1 (0.56) | GAACYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL14282209 | 0.80 | NOTUM (0.54) | CYP3A4CYP1A2ALDH1A1MAPTKMT2A | |
| SCHEMBL14221276 | 0.80 | IDO1 (0.59) | CYP3A4CYP2C19ALDH1A1MAPTMEN1 | |
| SCHEMBL14282213 | 0.78 | CYP17A1 (0.56) | CYP3A4CYP2C19ALDH1A1MAPTKMT2A | |
| SCHEMBL14282208 | 0.78 | RAB9A (0.53) | CYP3A4CYP1A2CYP2C19ALDH1A1MAPT | |
| SCHEMBL870689 | 0.78 | CYP3A4 (0.63) | GAACYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL14220860 | 0.77 | IDO1 (0.46) | CYP3A4CYP2C19ALDH1A1MAPTKMT2A | |
| SCHEMBL4672868 | 0.77 | RAB9A (0.67) | GAACYP1A2CYP2C9ALDH1A1MAPT | |
| SCHEMBL14282211 | 0.75 | NPBWR1 (0.46) | CYP3A4CYP1A2ALDH1A1MAPTKMT2A | |
| SCHEMBL14282214 | 0.74 | SMN1; SMN2 (0.43) | ALDH1A1MAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7320977-B2 | Fibrotic disorders; disorders characterized by harmful buildup of collagen and/or by excessive lysyl oxidase enzymatic activity | BAYER HEALTHCARE AG (DE) | 2008-01-22 | — | — | US | disclosed |
| US-7320977-B2 | Fibrotic disorders; disorders characterized by harmful buildup of collagen and/or by excessive lysyl oxidase enzymatic activity | BAYER HEALTHCARE AG (DE) | 2008-01-22 | — | — | US | disclosed |