Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | NPC1 | O15118 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.67 |
| ▸ | HTT | P42858 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.67 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.67 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.67 |
| ▸ | XBP1 | P17861 | 2/20 | 0.67 |
| ▸ | MITF | O75030 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731439 | 0.88 | RAB9A (0.60) | RAB9ANPC1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL3039419 | 0.85 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL19000700 | 0.85 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL29724940 | 0.85 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11729978 | 0.82 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL1461789 | 0.80 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11732101 | 0.80 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL13219469 | 0.79 | ALDH1A1 (0.54) | RAB9ANPC1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL11724179 | 0.79 | HTT (0.54) | RAB9ANPC1SMN1; SMN2HTTALDH1A1 | |
| SCHEMBL3022820 | 0.79 | NPBWR1 (0.63) | RAB9ANPC1SMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170173008-A1 | ANTIMICROBIAL AGENTS AND SCREENING METHODS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-06-22 | — | — | US | disclosed |
| US-20170173008-A1 | ANTIMICROBIAL AGENTS AND SCREENING METHODS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-06-22 | — | — | US | disclosed |
| EP-1497269-B1 | SUBSTITUTED 2-PHENYL-3(2H)-PYRIDAZINONES | BAYER HEALTHCARE AG (DE) | 2008-04-23 | — | — | EP | disclosed |
| US-7320977-B2 | Fibrotic disorders; disorders characterized by harmful buildup of collagen and/or by excessive lysyl oxidase enzymatic activity | BAYER HEALTHCARE AG (DE) | 2008-01-22 | — | — | US | disclosed |
| US-20060004015-A1 | Substituted 2-phenyl-3(2h)-pyridazinones | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2006-01-05 | — | — | US | disclosed |
| US-4002751-A | SLEEP INDUCERS, CNS DEPRESSANTS | SANDOZ, INC. (US) | 1977-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004015-A1 | Substituted 2-phenyl-3(2h)-pyridazinones | PIR, TPMT, PNPO | RAB9A 4468/4885NPC1 599/4885SMN1; SMN2 1763/4885 |
| US-20170173008-A1 | ANTIMICROBIAL AGENTS AND SCREENING METHODS | BAK1, DCLRE1B, BLVRB | RAB9A 3085/4885NPC1 2327/4885SMN1; SMN2 4088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.