Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14282925 | 0.91 | OPRD1 (0.45) | OPRD1OPRK1OPRM1SETD7HTR7 | |
| SCHEMBL14282939 | 0.80 | BACE1 (0.46) | — | |
| SCHEMBL14282904 | 0.73 | OPRD1 (0.50) | OPRD1OPRK1OPRM1SETD7HTR7 | |
| SCHEMBL14282906 | 0.71 | PRCP (0.44) | — | |
| SCHEMBL14282903 | 0.69 | CHRM2 (0.47) | OPRK1OPRM1 | |
| SCHEMBL4257154 | 0.68 | SETD7 (0.56) | OPRD1OPRK1OPRM1SETD7HTR7 | |
| SCHEMBL14198385 | 0.68 | SETD7 (0.65) | OPRD1OPRK1OPRM1SETD7HTR7 | |
| SCHEMBL14282965 | 0.67 | NPC1 (0.56) | OPRD1OPRK1OPRM1SETD7 | |
| SCHEMBL4563119 | 0.67 | OPRD1 (0.54) | OPRD1OPRK1OPRM1SETD7HTR7 | |
| SCHEMBL11036336 | 0.66 | SETD7 (0.53) | OPRD1OPRK1OPRM1SETD7HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7317026-B2 | Sleep disorders; side effect reduction ; antihistamine antagonist | HYPNION, INC. (US) | 2008-01-08 | — | — | US | disclosed |