Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15138014 | 0.93 | SMN1; SMN2 (0.35) | HRH3SMN1; SMN2CHRM1CHRM2CHRM4 | |
| SCHEMBL10036916 | 0.86 | CHRM1 (0.44) | HRH3SMN1; SMN2CHRM1CHRM2CHRM4 | |
| SCHEMBL13510860 | 0.85 | SMN1; SMN2 (0.40) | SMN1; SMN2CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL15315851 | 0.85 | HRH1 (0.44) | HRH3CHRM1CHRM2CHRM4HTR1A | |
| SCHEMBL13670291 | 0.85 | NAAA (0.45) | CHRM1CHRM2CHRM4HTR1ACHRM5 | |
| SCHEMBL10036917 | 0.84 | HRH1 (0.45) | HRH3SMN1; SMN2CHRM1CHRM2CHRM4 | |
| SCHEMBL19036251 | 0.83 | SMN1; SMN2 (0.40) | HRH3SMN1; SMN2CHRM1CHRM2CHRM4 | |
| SCHEMBL420320 | 0.83 | CHRM1 (0.46) | HRH3SMN1; SMN2CHRM1CHRM2CHRM4 | |
| SCHEMBL19036161 | 0.83 | HRH1 (0.41) | HRH3SMN1; SMN2CHRM1CHRM2CHRM4 | |
| SCHEMBL12650304 | 0.82 | SMN1; SMN2 (0.36) | HRH3SMN1; SMN2CHRM1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170258738-A1 | Multilayer Compositions, Coated Devices And Use Thereof | DEPARTMENT OF DEFENSE | 2017-09-14 | — | — | US | disclosed |
| US-9610252-B2 | Multilayer compositions, coated devices and use thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170258738-A1 | Multilayer Compositions, Coated Devices And Use Thereof | EPHA3, EPHA2, BDNF | HRH3 4823/4885SMN1; SMN2 493/4885CHRM1 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.